BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2

Bayne Rosemary A.; Donnachie Douglas J.; Kinnell Hazel L.; Childs Andrew J.; Anderson Richard A.

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BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2

机译：人体胎儿卵巢体细胞中的BMP信号传导以GREM1和GREM2以基因特异性的方式调节

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Do changes in the expression of bone morphogenetic proteins (BMPs) 2 and 4, and their antagonists Gremlin1 (GREM1) and Gremlin2 (GREM2) during human fetal ovarian development impact on BMP pathway activity and lead to changes in gene expression that may influence the fate and/or function of ovarian somatic cells?

机译：在人胎儿卵巢发育的影响下，对骨形态发生蛋白（BMPS）2和4，及其拮抗剂GREMLIN1（GREM1）和GREMLIN2（GREM2）的变化进行变化对BMP途径活性的影响，导致可能影响命运的基因表达的变化和/或卵巢体细胞的功能？

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来源
《Molecular human reproduction.》 |2016年第10期|共12页
作者
Bayne Rosemary A.; Donnachie Douglas J.; Kinnell Hazel L.; Childs Andrew J.; Anderson Richard A.;
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作者单位

Univ Edinburgh Queens Med Res Inst MRC Ctr Reprod Hlth Edinburgh EH16 4TJ Midlothian Scotland;

Univ Edinburgh Queens Med Res Inst MRC Ctr Reprod Hlth Edinburgh EH16 4TJ Midlothian Scotland;

Univ Edinburgh Queens Med Res Inst MRC Ctr Reprod Hlth Edinburgh EH16 4TJ Midlothian Scotland;

Royal Vet Coll Dept Comparat Biomed Sci London NW1 0TU England;

Univ Edinburgh Queens Med Res Inst MRC Ctr Reprod Hlth Edinburgh EH16 4TJ Midlothian Scotland;

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原文格式 PDF
正文语种 eng
中图分类呼吸生理;
关键词
BMP; BMP antagonist; human fetal ovary; ovarian somatic cell; pre-granulosa cell; ovarian development;

机译：BMP;BMP拮抗剂;人胎卵巢;卵巢体细胞;颗粒粒细胞;卵巢发育;

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1. BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2 [J] . Bayne Rosemary A., Donnachie Douglas J., Kinnell Hazel L., Molecular human reproduction. . 2016,第9a10期

机译：GREM1和GREM2以基因特异性方式调节人胎儿卵巢体细胞中的BMP信号传导
2. Activin signals via SMAD2/3 between germ and somatic cells in the human fetal ovary and regulates kit ligand expression. [J] . Coutts SM, Childs AJ, Fulton N Developmental biology . 2008,第1期

机译：激活素通过人类胎儿卵巢中生殖细胞和体细胞之间的SMAD2 / 3发出信号，并调节试剂盒配体的表达。
3. Activin signals via SMAD2/3 between germ and somatic cells in the human fetal ovary and regulates kit ligand expression [J] . Shiona M. Coutts, Andrew J. Childs, Norma Fulton, Developmental biology . 2008,第1期

机译：激活素通过人胎儿卵巢生殖细胞和体细胞之间的SMAD2 / 3发出信号，并调节试剂盒配体的表达
4. Pluripotent Unrestricted Somatic Stem Cells (USSC) from cord blood generate cardiomyocytes and Purkinje fibers in vivo applying the pre-immune fetal sheep model [C] . S. Sensken, J. A. Airey, E. Zanjani, Nordrhein-Westfa?lische Akademie der Wissenschaften . 2005

机译：多能不受限制的体细胞干细胞（USSC）从脐带血中产生心肌细胞和Purkinje纤维的体内应用预防胎儿绵羊模型
5. Nicotine and TNF alpha, modulators of T cell signaling-effects on T cell development in fetal thymus organ culture. [D] . Middlebrook, Aaron Jacob. 2004

机译：尼古丁和TNFα，T细胞信号传导调节剂对胎儿胸腺器官培养中T细胞发育的影响。
6. BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2 [O] . Rosemary A. Bayne, Douglas J. Donnachie, Hazel L. Kinnell, -1

机译：GREM1和GREM2以基因特异性方式调节人胎儿卵巢体细胞中的BMP信号传导
7. Activin signals via SMAD2/3 between germ and somatic cells in the human fetal ovary and regulates kit ligand expression [O] . Coutts Shiona M., Childs Andrew J., Fulton Norma, 2008

机译：激活素通过SMAD2 / 3在人胎儿卵巢的生殖细胞和体细胞之间发出信号，并调节试剂盒配体的表达

BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2

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