Other Breast Neoplasms

摘要

Angiosarcoma Introduction/Epidemiology: Angiosarcomas of the breast are relatively rare, but they represent the second most common mesenchymal malignancy in the breast after high-grade phyllodes tumor. They are classically subdivided into primary and secondary angiosarcomas based on their clinical presentation. Primary angiosarcomas are rare and may occur in younger women, usually in the third or fourth decade of life. They develop deeply in the breast parenchyma as painless masses or diffuse breast enlargement. Secondary angiosarcomas arise in the breast skin or in the chest wall in patients who underwent breast surgery, as a consequence of lymphedema after axillary dissection or, most commonly nowadays, after conservative breast surgery (lumpectomy or quadrantectomy for breast carcinoma) followed by radiation treatment [Mery et al, 2009]. These lesions are frequently multifocal and may be preceded by atypical vascular proliferation in the breast skin, appearing as small, reddish intradermal nodules over the treated area.