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Dysregulation of the Causative Genes for Hereditary Parkinsonism in the Midbrain in Parkinson's Disease

机译:帕金森病中脑膜中遗传性帕金森主义的致病基因的失调

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摘要

Background and Objectives: Many hereditary movement disorders with complex phenotypes without a locus symbol prefix for familial PD present as parkinsonism; however, the dysregulation of genes associated with these phenotypes in the SNpc of PD patients has not been systematically studied.
机译:背景和目标:许多遗传性运动障碍,其具有复杂的表型,没有轨迹符号前缀为帕金森主义的家族性PD; 然而,没有系统地研究了与PD患者SNPC中这些表型相关的基因的失调。

著录项

  • 来源
    《Movement disorders》 |2017年第8期|共10页
  • 作者单位

    Hallym Univ ILSONG Inst Life Sci 15 Gwanpyeong Ro 170 Beon Gil Anyang 14066 South Korea;

    Hallym Univ Dept Comp Engn Hallymdaehak Gil Chunchon 24252 Gangwon Do South Korea;

    Hallym Univ Dept Comp Engn Hallymdaehak Gil Chunchon 24252 Gangwon Do South Korea;

    Hallym Univ Hallym Inst Translat Genom &

    Bioinformat Med Ctr Anyang South Korea;

    Hallym Univ ILSONG Inst Life Sci 15 Gwanpyeong Ro 170 Beon Gil Anyang 14066 South Korea;

    Hallym Univ ILSONG Inst Life Sci 15 Gwanpyeong Ro 170 Beon Gil Anyang 14066 South Korea;

    Hallym Univ Hallym Inst Translat Genom &

    Bioinformat Med Ctr Anyang South Korea;

    Hallym Univ Dept Neurol Chuncheon Sacred Heart Hosp Coll Med Chunchon South Korea;

    Hallym Univ Dept Neurol Sacred Heart Hosp Coll Med Anyang South Korea;

    Hallym Univ Dept Neurol Dongtan Sacred Heart Hosp Coll Med Dongtan South Korea;

    Hallym Univ Dept Neurol Sacred Heart Hosp Coll Med Anyang South Korea;

    Hallym Univ Dept Elect Engn Chunchon South Korea;

    Hallym Univ Dept Comp Engn Hallymdaehak Gil Chunchon 24252 Gangwon Do South Korea;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 神经病学;
  • 关键词

    Parkinson's disease; microarray; gene set enrichment analysis; hereditary movement disorders; PPP2R2B;

    机译:帕金森病;微阵列;基因设定富集分析;遗传运动障碍;PPP2R2B;

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