High contrast measurement of nanoparticle with polarization interferometric nonlinear confocal microscope

摘要

Polarization interferometric nonlinear confocal microscope has been developed to observe a submicron size object in high contrast. The microscope succeeded in resolving the inside of a 200-nm-diameter polymeric nanoparticle. According to CTF (contrast transfer function) measurement and three-dimensional imaging with the microscope, the best spatial resolution for the microscope is 10 nm.