The administration of adjuvant chemo(-immuno) therapy in the post ACOSOG-Z0011 era; a population based study

摘要

Purpose: The ACOSOG-Z0011-study has resulted in a trend to a more conservative treatment of the axilla for selected sentinel-node-positive patients. However, axillary nodal involvement has always been an important factor for tumor staging and tailoring adjuvant chemotherapy plans. This study evaluates the impact of omitting completion axillary lymph node dissection (cALND) on the administration of adjuvant chemo (-immuno)therapy in Dutch clinical T1-2N0M0 (cTl-2N0M0) sentinel-node-positive breast cancer patients.