An efficient Fourier ptychographic microscopy method based on optimized pattern of LED angle illumination

摘要

Considering angle diversity and synthetic aperture, Fourier ptychographic microscopy (FPM) could address contradiction of high resolution and wide field of view. However, in the conventional FPM method, large capture quantity leads to poor efficiency. So, an efficient FPM method based on optimized pattern of LED angle illu-mination is proposed. Firstly, from position relationship between the LED, aperture and sample, we obtain theoretical expandable spectrum range and the spectrum distribution in Fourier space of all LEDs. Secondly, use image quality assessment methods to extract differential expressions between an arbitrary LED illumination and full LEDs illumination. Thirdly, the optimized angle illumination strategy is achieved according to analysis of different expressions. Based on this method, we design a rhombus-based illumination method for LED array to accelerate the FPM efficiency. Finally, we validate the effectiveness and efficiency of our method with both simulated and real experiments. The results indicate that our method can effectively improve efficiency for FPM without sacrificing image reconstruction quality.