Leptin, appetite and weight rebound in overweight/obesity individuals undertook weight loss program using a low calorie diet with or without exercise

摘要

BACKGROUND:It has been suggested that leptin plays an important role in regulating in energy expenditure and appetite. OBJECTIVE:The aim of this study was to evaluate the effect of a low calorie diet with or without combined exercises on leptin, appetite, and weight rebound. METHODS:This is an experimental study and 63 subjects were divided into two groups: a low calorie diet group (LCD) and a low calorie diet with training group (LCD+training). Appetite, anthropometric measures, dietary intake and plasma leptin level were measured before and after the intervention (8 weeks). Body weight was measured 4 weeks after the intervention was ended. RESULTS:The appetite ratings including sensation of hunger, satiety, fullness, and desire to eat were unchanged in both groups (P?>?0.05). Energy and carbohydrate intake were correlated with hunger, satiety and fullness before the intervention (P?