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Reflux Precipitation Polymerization: A New Platform for the Preparation of Uniform Polymeric Nanogels for Biomedical Applications

机译：回流沉淀聚合：用于制备均匀聚合物纳米凝胶的新平台，用于生物医学应用

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Abstract >Reflux precipitation polymerization (RPP) represents an effective approach that enables to prepare various types of polymeric nanogels with precise control over the morphology and structure. Owing to facile loading or modification by a variety of functional moieties, rationally designed nanogels pose the possibility to attain a platform for tailoring functional properties that could be widely used for various biomedical applications, such as multifunctional drug delivery, enrichment of functional peptides, separation of specific proteins, as well as detection of circulating tumor cells. This feature article highlights RPP as a promising polymerization strategy that provides access to facile generation of modular nanostructures or multifunctional properties in a diverse range of biomedical applications, proving that RPP has great potential to become one of the most attractive polymerization techniques in polymer chemistry. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“Main”XML：Lang =“en”> <标题类型=“main”>摘要</标题> >回流沉淀聚合（RPP）代表一种能够制备各种类型的聚合物纳米凝胶的有效方法精确控制形态和结构。由于各种功能部分的载荷或改性，理性设计的纳米凝块可以获得可用于剪裁功能性的平台，可以广泛用于各种生物医学应用，例如多功能药物递送，富集功能肽的富集，分离特异性蛋白质，以及循环肿瘤细胞的检测。该特征文章突出了RPP作为有希望的聚合策略，可提供对模块化纳米结构或多功能性质的进一步产生的，以各种各样的生物医学应用，证明RPP具有很大的潜力，成为聚合物化学中最具吸引力的聚合技术之一。< / p> </ abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-24307/'>《Macromolecular bioscience》</a> <b style="margin: 0 2px;">|</b><span>2018年第8期</span><b style="margin: 0 2px;">|</b><span>共11页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Fan Mingliang&option=202" target="_blank" rel="nofollow">Fan Mingliang;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Wang Fang&option=202" target="_blank" rel="nofollow">Wang Fang;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Wang Changchun&option=202" target="_blank" rel="nofollow">Wang Changchun;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>State Key Laboratory of Molecular Engineering of PolymersFudan University220 Han Dan Road Shanghai 200433 China;</p> <p>State Key Laboratory of Molecular Engineering of PolymersFudan University220 Han Dan Road Shanghai 200433 China;</p> <p>State Key Laboratory of Molecular Engineering of PolymersFudan University220 Han Dan Road Shanghai 200433 China;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/1185.html" title="高分子化学（高聚物）">高分子化学（高聚物）;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=cell detection&option=203" rel="nofollow">cell detection;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=drug delivery&option=203" rel="nofollow">drug delivery;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=nanogels&option=203" rel="nofollow">nanogels;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=proteins and peptide enrichment&option=203" rel="nofollow">proteins and peptide enrichment;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=reflux precipitation polymerization&option=203" rel="nofollow">reflux precipitation polymerization;</a> </p> <div class="translation"> 机译：细胞检测;药物递送;纳米凝胶;蛋白质和肽富集;回流沉淀聚合; 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