Expert's comment concerning Grand Rounds case entitled 'total spondylectomy for solitary bone plasmacytoma of the lumbar spine in a young woman. A case report and review of the literature' (by N. von der Hoeh, S.K. Tschoeke, J. Gulow, A. Voelker, U. Siebolts and C.-E. Heyde).

摘要

None of the hydrogel configurations was able to regenerate biofunctionality of the intervertebral disc. This might presumably be caused by hydrogel extrusion. Great importance should be given to the development of annulus sealants, which effectively exploit the potential of (cell-seeded) hydrogels for biological disc regeneration and restoration of intervertebral disc functioning.