首页> 外文期刊>European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) >Randomised phase II study of panitumumab plus irinotecan versus cetuximab plus irinotecan in patients with KRAS wild-type metastatic colorectal cancer refractory to fluoropyrimidine, irinotecan and oxaliplatin (WJOG 6510G)
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Randomised phase II study of panitumumab plus irinotecan versus cetuximab plus irinotecan in patients with KRAS wild-type metastatic colorectal cancer refractory to fluoropyrimidine, irinotecan and oxaliplatin (WJOG 6510G)

机译:Panitumumab Plus in Irinotecan与氟丙二屈氏蛋白酶酸难以氟嘧啶,Irinotecan和Oxaliplatin(Wjog 6510g)患者的随机素in inerucotecan对伊喹仑(Cetuximab)对氨基替康酸的氨管

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摘要

Background: Cetuximab has been shown to be clinically active when given in combination with irinotecan in patients with irinotecan-refractory metastatic colorectal cancer (mCRC). However, it has remained unclear whether panitumumab is effective when combined with irinotecan. We compared efficacies of both regimens in this randomised phase II study.
机译:背景:当伊替康 - 难治转移结直肠癌(MCRC)的患者组合时,西列妥昔单抗被证明是临床活性的。 然而,它仍然不清楚Panitumumab与Irinotecan结合时是否有效。 我们在该随机期II研究中比较了两种方案的疗效。

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