Focusing on Target Safety: The development of new medicines is long, laborious, costly, and far too often results in failure, but the rise of artificial intelligence may be the solution to many, if not all, of these issues

摘要

Despite the increase in drug approvals in recent years, drug discovery and development remain an uncertain and costly endeavour with depressingly high rates of failure (1).The era of Big Data and artificial intelligence (Al) offers the potential to manipulate huge amounts of data and discern patterns, offering scientists better insights and supporting better decisions than previously. Consequently, stakeholders across all disciplines are exploring ways to incorporate these powerful new approaches into their thinking. The identification of better drug targets, safer and more effective molecules, and improved patient selection should lead to better drugs as well as greater efficiency and decreased costs.