Quantitative assessment of optic nerve in patients with Leber's hereditary optic neuropathy using reduced field-of-view diffusion tensor imaging

摘要

Purpose: To quantitatively analyze the optic nerve alterations in chronic Leber's hereditary optic neuropathy (LHON) using reduced field-of-view diffusion tensor imaging (rFOV-DTI) and evaluate the correlation of diffusion parameters with visual functional and peripapillary retinal nerve fiber layer (RNFL) thickness.