Performance of Amperometric Platinized‐Nafion Based Gas Phase Sensor for Determining Nitric Oxide (NO) Levels in Exhaled Human Nasal Breath

Zajda Joanna; Schmidt Nicholas J.; Zheng Zheng; Wang Xuewei; Meyerhoff Mark E.

摘要

Abstract > Nitric oxide (NO) levels in exhaled breath are a non‐invasive marker that can be used to diagnose various respiratory diseases and monitor a patient's response to given therapies. A portable and inexpensive device that can enable selective NO concentration measurements in exhaled breath samples is needed. Herein, the performance of an amperometric Pt‐Nafion‐based gas phase sensor for detection of NO in exhaled human nasal breath is examined. Enhanced selectivity over carbon monoxide and ammonia is achieved via an in‐line zinc oxide‐based filter. Exhaled nasal NO levels measured in 21 human samples with the sensor are shown to correlate well with those obtained using a chemiluminescence reference method (R 2 =0.9836). </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“Main”XML：Lang =“en”> <标题类型=“main”>呼出呼吸中的抽象</标题> >一氧化物（NO）水平是可以使用的非侵入性标记诊断各种呼吸系统疾病并监测患者对给定疗法的反应。需要在呼出的呼吸样品中实现选择性的便携式和廉价的装置。这里，检查用于检测在呼出的人鼻呼吸中的水平的PT-Nafion基气相传感器的性能。通过在线氧化锌基过滤器实现了通过一氧化碳和氨的增强的选择性。呼出的鼻腔在21例人样品中没有测量的鼻腔没有传感器测量的水平与使用化学发光参考法（R <SUP> 2 </ sup> = 0.9836）获得的那些相互作用。 </ p> </ abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-22546/'>《Electroanalysis》</a> <b style="margin: 0 2px;">|</b><span>2018年第8期</span><b style="margin: 0 2px;">|</b><span>共6页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Zajda Joanna&option=202" target="_blank" rel="nofollow">Zajda Joanna;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Schmidt Nicholas J.&option=202" target="_blank" rel="nofollow">Schmidt Nicholas J.;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Zheng Zheng&option=202" target="_blank" rel="nofollow">Zheng Zheng;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Wang Xuewei&option=202" target="_blank" rel="nofollow">Wang Xuewei;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Meyerhoff Mark E.&option=202" target="_blank" rel="nofollow">Meyerhoff Mark E.;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of ChemistryUniversity of Michigan930 North University Avenue Ann Arbor MI 48109-1055 USA.;</p> <p>Department of ChemistryUniversity of Michigan930 North University Avenue Ann Arbor MI 48109-1055 USA.;</p> <p>Department of ChemistryUniversity of Michigan930 North University Avenue Ann Arbor MI 48109-1055 USA.;</p> <p>Department of ChemistryUniversity of Michigan930 North University Avenue Ann Arbor MI 48109-1055 USA.;</p> <p>Department of ChemistryUniversity of Michigan930 North University Avenue Ann Arbor MI 48109-1055 USA.;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/4817.html" title="电化学、电解、磁化学">电化学、电解、磁化学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=amperometric gas-phase sensor&option=203" rel="nofollow">amperometric gas-phase sensor;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=nitric oxide&option=203" rel="nofollow">nitric oxide;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=nasal breath&option=203" rel="nofollow">nasal breath;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Nafion&option=203" rel="nofollow">Nafion;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=zinc oxide&option=203" rel="nofollow">zinc oxide;</a> </p> <div class="translation"> 机译：安培测力气相传感器;一氧化氮;鼻呼吸;Nafion;氧化锌; 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