Effect of combined treatment of radiation and tissue-specific recombinant oncolytic adenovirus on bladder cancer cells

Zhang Hongjuan; Wang Fang; Mao Chunjie; Zhang Zuncheng; Fu Shengjun; Lu Jianzhong; Zhai Zhenxing; Li Renju; Li Shuwen; Rodriguez Ron; Wang Zhiping

首页> 外文期刊>International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations >Effect of combined treatment of radiation and tissue-specific recombinant oncolytic adenovirus on bladder cancer cells

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Effect of combined treatment of radiation and tissue-specific recombinant oncolytic adenovirus on bladder cancer cells

机译：结合治疗辐射和组织特异性重组溶血性腺病毒对膀胱癌细胞的影响

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Purpose: Gene therapy combined with radiation has shown promising potential for the treatment of tumors. This paper aimed to clarify the synergistic effect of radiotherapy combined with the bladder cancer tissue-specific oncolytic adenovirus (Ad-PSCAE-UPII-E1A) on bladder cancer cells and to study the underlying synergy mechanisms of the combined treatment.

机译：目的：基因治疗结合辐射表明了治疗肿瘤的有希望的潜力。本文旨在阐明放疗的协同效应与膀胱癌组织特异性腺瘤病毒（Ad-Pscae-Upi-E1a）相结合对膀胱癌细胞，并研究合并治疗的潜在协同机制。

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来源
《International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations》 |2017年第2期|共10页
作者
Zhang Hongjuan; Wang Fang; Mao Chunjie; Zhang Zuncheng; Fu Shengjun; Lu Jianzhong; Zhai Zhenxing; Li Renju; Li Shuwen; Rodriguez Ron; Wang Zhiping;
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作者单位

Lanzhou Univ Hosp 2 Inst Urol Urol Clin Ctr Gansu Prov Key Lab Gansu Prov 82 Cuiying Men;

Lanzhou Univ Sch Basic Med Sci Lanzhou Peoples R China;

Tianjin Med Univ Gen Hosp Tianjin Peoples R China;

Tianjin Med Univ Hosp 2 Tianjin Peoples R China;

Lanzhou Univ Hosp 2 Inst Urol Urol Clin Ctr Gansu Prov Key Lab Gansu Prov 82 Cuiying Men;

Lanzhou Univ Hosp 2 Inst Urol Urol Clin Ctr Gansu Prov Key Lab Gansu Prov 82 Cuiying Men;

Lanzhou Univ Hosp 2 Inst Urol Urol Clin Ctr Gansu Prov Key Lab Gansu Prov 82 Cuiying Men;

Lanzhou Univ Hosp 2 Inst Urol Urol Clin Ctr Gansu Prov Key Lab Gansu Prov 82 Cuiying Men;

Lanzhou Univ Hosp 2 Inst Urol Urol Clin Ctr Gansu Prov Key Lab Gansu Prov 82 Cuiying Men;

Univ Texas Hlth Sci Ctr San Antonio Dept Urol San Antonio TX 78229 USA;

Lanzhou Univ Hosp 2 Inst Urol Urol Clin Ctr Gansu Prov Key Lab Gansu Prov 82 Cuiying Men;

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原文格式 PDF
正文语种 eng
中图分类放射医学;
关键词
Bladder cancer; gene therapy; oncolytic adenovirus; radiation therapy;

机译：膀胱癌;基因治疗;溶瘤腺病毒;放射治疗;

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专利

1. Effect of combined treatment of radiation and tissue-specific recombinant oncolytic adenovirus on bladder cancer cells [J] . Zhang Hongjuan, Wang Fang, Mao Chunjie, International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations . 2017,第2期

机译：结合治疗辐射和组织特异性重组溶血性腺病毒对膀胱癌细胞的影响
2. Biodistribution and safety assessment of bladder cancer specific recombinant oncolytic adenovirus in subcutaneous xenografts tumor model in nude mice [J] . WangF., WangZ., TianH., Current gene therapy . 2012,第2期

机译：膀胱癌特异性重组溶瘤腺病毒在裸鼠皮下异种移植肿瘤模型中的生物分布和安全性评估
3. Bladder cancer therapy using combined proliferating cell nuclear antigen antisense oligonucleotides and recombinant adenovirus p53 [J] . ZHU Zhaohui, XING Shian, LIN Chen, Chinese Medical Journal . 2003,第12期

机译：联合使用增殖细胞核抗原反义寡核苷酸和重组腺病毒p53进行膀胱癌治疗
4. Herbal Tea extract combined with light induced significant in vitro cytotoxicity of human bladder cancer cells [C] . U.Nseyo, A.Kim, N.E.Stavropoulos, Photonic Therapeutics and Diagnostics; Progress in Biomedical Optics and Imaging; vol.6, no.1 . 2005

机译：凉茶提取物与光结合对人膀胱癌细胞具有明显的体外细胞毒性
5. Gene therapy approach utilizing adenovirus to deliver the pro-apoptotic gene, Bax, for tissue-specific treatment of prostate cancer. [D] . Lowe, Stephanie Lewis. 2002

机译：利用腺病毒的基因治疗方法来传递促凋亡基因Bax，用于前列腺癌的组织特异性治疗。
6. A novel bladder cancer - specific oncolytic adenovirus by CD46 and its effect combined with cisplatin against cancer cells of CAR negative expression [O] . Wenjuan Cao, Junqiang Tian, Chong Li, 2017

机译：CD46新型膀胱癌特异性溶瘤腺病毒及其与顺铂联合对抗CAR阴性细胞的作用。
7. Biodistribution and Safety Assessment of Bladder Cancer Specific Recombinant Oncolytic Adenovirus in Subcutaneous Xenografts Tumor Model in Nude Mice [O] . Fang Wang, Zhiping Wang, Hongwei Tian, 2012

机译：裸鼠皮下异种移植肿瘤模型中膀胱癌特异性重组溶血性腺病毒的生物分布和安全评估

Effect of combined treatment of radiation and tissue-specific recombinant oncolytic adenovirus on bladder cancer cells

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