A Novel Method for In Situ Synthesis of Nanostructure Hydroxyapatite-nylon 66 Composites in Tissue Engineering

摘要

An interfacial polymerization method for nylon 66 was adapted to produce nanostrue-tured composites with nanohydroxyapatite (n-HA) via in situ polymerization. Nylon 66 was synthesized in n-HA slurry to increase homogeneity and biocompatibility. Synthesis powders was characterized by XRD, TEM, TGA, and FT-IR analysis. The results showed a uniform dispersion in composites, whereas needle-like, n-HA crystals dispersed in condensed polymer matrix. The samples were immersed in SBF for bioactiv-ity tests in different periods, and results were monitored by SEM and EDX in terms of forming an apatite layer. The mechanical properties of the n-HA/nylon66 nanocomposites are discussed in terms of n-HA loading.