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The Effect of Tracheal Stenosis at Different Locations and Sizes on Airflow in the Trachea and Main Bronchi: A Numerical Modeling Analysis

机译:不同位置和大小的气管狭窄对气管和主支气管气流的影响:数值模型分析

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摘要

The location and size of tracheal stenosis are among the major factors that contribute significantly to the breathing difficulties. Hence, this study aims to establish correlation between the location and size of the stenosis to the possibility of breathing difficulties. This work used ideal trachea model based on realistic trachea model derived from Computed Tomography (CT) scan images. The stenosis was patched to the healthy trachea models at regular locations and sizes as proposed by medical practitioners. The changes in the flow behavior due to the different sizes and locations of the stenosis were then examined to determine the pattern of possible breathing difficulties. The present simulation confirms that the overall flow behavior could be significantly affected if the size of stenosis is more than 60% for location far from the bifurcation region, and at size of 50% for location close to the bifurcation region. The outcomes of this study may help the medical practitioners and researchers to understand how dramatic increase in pressure drops occurs inside the trachea and main bronchi with the presence of stenosis at different location and size.
机译:气管狭窄的位置和大小是导致呼吸困难的主要因素。因此,本研究旨在确定狭窄部位和大小与呼吸困难的可能性之间的相关性。这项工作使用基于从计算机断层扫描(CT)扫描图像得出的真实气管模型的理想气管模型。根据医生的建议,将狭窄部位固定在正常位置和大小的健康气管模型上。然后检查由于狭窄大小和位置不同而引起的流动行为变化,以确定可能出现呼吸困难的模式。本模拟结果证实,如果狭窄的大小在远离分叉区域的位置处大于60%,而狭窄的大小在靠近分叉区域的位置处大于50%,则总体流动行为会受到显着影响。这项研究的结果可能有助于医学从业人员和研究人员了解在不同位置和大小存在狭窄的情况下,气管和主支气管内部压力下降的急剧增加情况。

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