Number of prostate cancer risk alleles may identify possibly 'insignificant' disease.

Helfand BT; Loeb S; Kan D; Catalona WJ

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Number of prostate cancer risk alleles may identify possibly 'insignificant' disease.

机译：前列腺癌风险等位基因的数量可能确定可能“无关紧要”的疾病。

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OBJECTIVE: To determine whether the cumulative effects of five prostate cancer risk alleles (three single-nucleotide polymorphisms [SNPs] on chromosome 8Q24 and two SNPs on chromosome 17a) could help to identify possibly 'insignificant' disease. MATERIALS AND METHODS: We genotyped 629 men of European ancestry who underwent radical prostatectomy at our institution between 2002 and 2007. Possibly 'insignificant' CaP was defined using the Ohori criteria (organ-confined, tumour volume <0.5 mL, Gleason pattern

机译：目的：确定五个前列腺癌风险等位基因（第8Q24号染色体上的三个单核苷酸多态性[SNPs]和第17a号染色体上的两个SNPs）的累积效应是否有助于识别可能“无关紧要”的疾病。材料与方法：我们对2002年至2007年间在我们机构接受过前列腺癌根治术的629名欧洲血统男性进行了基因分型。可能使用Ohori标准（器官受限，肿瘤体积<0.5 mL，格里森模式

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《BJU international》 |2010年第11期|共5页
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Helfand BT; Loeb S; Kan D; Catalona WJ;
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中图分类泌尿科学（泌尿生殖系疾病）;
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1. Number of prostate cancer risk alleles may identify possibly 'insignificant' disease. [J] . Helfand BT, Loeb S, Kan D, BJU international . 2010,第11期

机译：前列腺癌风险等位基因的数量可能确定可能“无关紧要”的疾病。
2. Number of prostate cancer risk alleles may identify possibly ‘insignificant’ disease [J] . li id=cr1Brian T. Helfand li id=cr2Stacy Loeb li id=cr3Donghui Kan li id=cr4William J. Catalona BJU International . 2010,第11期

机译：前列腺癌风险等位基因的数量可能识别出可能“微不足道”的疾病
3. Can the core length involved with prostate cancer identify clinically insignificant disease in low risk patients diagnosed on the basis of a single positive core? [J] . Lee AK, Doytchinova T, Chen MH, Urologic oncology . 2003,第2期

机译：前列腺癌涉及的核心长度是否可以在基于单个阳性核心诊断的低风险患者中识别出临床上无关紧要的疾病？
4. A combination of intra- and peri-tumoral deep features from prostate bi-parametric MRI can distinguish clinically significant and insignificant prostate cancer [C] . Amogh Hiremath, Rakesh Shiradkar, Nathaniel Braman, Medical Imaging Conference . 2020

机译：前列腺双参数MRI的肿瘤内和肿瘤周围深部特征的组合可以区分临床上显着和不重要的前列腺癌
5. Diet and prostate cancer: Investigating the relationship between risk of prostate cancer and serum concentrations of individual carotenoids, selenium, and alpha-tocopherol in United States Black and White men. [D] . Vogt, Tara Michelle. 2001

机译：饮食和前列腺癌：研究美国黑人和白人中前列腺癌风险与个体类胡萝卜素，硒和α-生育酚的血清浓度之间的关系。
6. Number of prostate cancer risk alleles may identify possibly ‘insignificant’ disease [O] . Brian T. Helfand, Stacy Loeb, Donghui Kan, -1

机译：前列腺癌风险等位基因可能识别可能的微不足道的疾病
7. ABO blood group alleles and prostate cancer risk: Results from the breast and prostate cancer cohort consortium (BPC3) [O] . Sarah C. Markt, Irene M. Shui, Robert H. Unger, 2015

机译：ABO血型等位基因和前列腺癌风险：乳腺癌和前列腺癌队列的结果（BPC3）

Number of prostate cancer risk alleles may identify possibly 'insignificant' disease.

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