Impact statement: A clinical decision support system using multi-modality imaging data for disease diagnosis

摘要

Among more than 200 headache syndromes, migraine is the predominant disease that affects nearly 14% of the population. The diagnosis is exclusively a clinical one, as no unequivocal diagnostic test exists. Given that migraine is one of the most prevalent neurological disorders, with a considerable disability and low quality of life (GBD, 2017), researchers worldwide have strived for several decades to find a clear diagnostic biomarker. Owing to novel neuroimaging approaches and evaluation methods, a range of possibilities for exploring brain differences in migraine patients have become available (Davis et at, 2017). And although neuroimaging and especially functional neuroimaging and network connectivity changes enabled us to unravel the pathogenesis behind migraine (Schwedt et al, 2015), no single technique was sufficient to provide a positive biomarker.