A Third Dose of Measles-Mumps-Rubella Vaccine to Improve Immunity Against Mumps in Young Adults

Kaaijk Patricia; Wijmenga-Monsuur Alienke J.; van Houten Marlies A.; Veldhuijzen Irene K.; ten Hulscher Hinke I; Kerkhof Jeroen; van der Klis Fiona R.; van Binnendijk Rob S.

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A Third Dose of Measles-Mumps-Rubella Vaccine to Improve Immunity Against Mumps in Young Adults

机译：第三剂麻疹-Mumps-rubella疫苗，以提高年轻成年人腮腺炎的免疫力

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Background. Waning of vaccine-induced immunity is considered to play a central role in the reemergence of mumps among vaccinated young adults. The aim of the present study was to investigate antibody responses and safety of a third dose of measles-mumps-rubella vaccine (MMR-3) in 150 young adults. Antibody levels were related to a surrogate of protection based on preoutbreak serum antibody levels in 31 persons with and 715 without serological evidence of mumps.

机译：背景。疫苗诱导的免疫力被认为是在接种疫苗的年轻成年人中的腮腺炎的崩溃中起着核心作用。本研究的目的是在150名年轻成年人中调查抗体反应和第三剂量麻疹-Mumps-Surbella疫苗（MMR-3）的安全性。抗体水平与基于31人的前血清抗体水平的保护水平有关，没有腮腺炎的血清学证据。

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来源
《Autonomic neuroscience: basic & clinical 》 |2019年第1期| 共8页
作者
Kaaijk Patricia; Wijmenga-Monsuur Alienke J.; van Houten Marlies A.; Veldhuijzen Irene K.; ten Hulscher Hinke I; Kerkhof Jeroen; van der Klis Fiona R.; van Binnendijk Rob S.;
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作者单位

Natl Inst Publ Hlth &

Environm Ctr Infect Dis Control POB 1 NL-3720 BA Bilthoven Netherlands;

Natl Inst Publ Hlth &

Environm Ctr Infect Dis Control POB 1 NL-3720 BA Bilthoven Netherlands;

Spaarne Hosp Dept Pediat Hoofddorp Netherlands;

Natl Inst Publ Hlth &

Environm Ctr Infect Dis Control POB 1 NL-3720 BA Bilthoven Netherlands;

Natl Inst Publ Hlth &

Environm Ctr Infect Dis Control POB 1 NL-3720 BA Bilthoven Netherlands;

Natl Inst Publ Hlth &

Environm Ctr Infect Dis Control POB 1 NL-3720 BA Bilthoven Netherlands;

Natl Inst Publ Hlth &

Environm Ctr Infect Dis Control POB 1 NL-3720 BA Bilthoven Netherlands;

Natl Inst Publ Hlth &

Environm Ctr Infect Dis Control POB 1 NL-3720 BA Bilthoven Netherlands;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学 ;
关键词
Mumps; measles-mumps-rubella (MMR) vaccine; immunogenicity; antibody response; safety;

机译：腮腺炎;麻疹 - 腮腺炎 - 风疹（MMR）疫苗;免疫原性;抗体应答;安全;

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专利

1. A Third Dose of Measles-Mumps-Rubella Vaccine to Improve Immunity Against Mumps in Young Adults [J] . Kaaijk Patricia, Wijmenga-Monsuur Alienke J., van Houten Marlies A., The Journal of Infectious Diseases . 2020 ,第6期

机译：第三剂麻疹-mumps-rubella疫苗，以改善年轻成年人腮腺炎的免疫力
2. Mumps Antibody Response in Young Adults After a Third Dose of Measles-Mumps-Rubella Vaccine [J] . Amy Parker Fiebelkorn, Cheryl Zhang, Daoling Bi, Open Forum Infectious Diseases . 2014 ,第3期

机译：麻疹-腮腺炎-风疹疫苗第三剂后年轻人的腮腺炎抗体反应
3. Rubella virus neutralizing antibody response after a third dose of measles-mumps-rubella vaccine in young adults [J] . Huong Q. McLean, Amy Parker Fiebelkorn, Adaeze Ogee-Nwankwo, Vaccine . 2018 ,第38期

机译：Rubella病毒中和在年轻成年人的第三剂麻疹 - 腮腺炎 - 风疹疫苗后中和抗体反应
4. THE EFFICACY AND DURATION OF IMMUNITY OF STELLAMUNE ONE ~RlA SINGLE DOSE MYCOPLASMA HYOPNEUMONIAE VACCINE FOR YOUNG PIGS [C] . A Dawson, S Thevasagayam, SC Smith, Congress of the International Pig Veterinary Society . 2002

机译：Stellamune One〜rla单剂量支原体支原体的疗效和持续时间为幼猪疫苗疫苗
5. Low dose tolerance vaccine platform, reovirus protein sigma 1 and treatment of autoimmunity. [D] . Rynda, Agnieszka. 2008

机译：低剂量耐受性疫苗平台，呼肠孤病毒蛋白sigma 1和自身免疫治疗。
6. Measles virus neutralizing antibody response cell-mediated immunity and IgG antibody avidity before and after a third dose of measles-mumps-rubella vaccine in young adults [O] . Amy Parker Fiebelkorn, Laura A. Coleman, Edward A. Belongia, -1

机译：年轻人第三次接种麻疹-腮腺炎-风疹疫苗前后麻疹病毒中和抗体反应细胞介导的免疫力和IgG抗体亲和力
7. A Third Dose of Measles-Mumps-Rubella Vaccine to Improve Immunity Against Mumps in Young Adults [O] . Patricia Kaaijk, Alienke J Wijmenga-Monsuur, Marlies A van Houten, 2019

机译：第三剂麻疹-mumps-rubella疫苗，以改善年轻成年人腮腺炎的免疫力
8. Risk of Measles, Mumps, and Varicella among Young Adults: A Serosurvey of US Navyand Marine Corps Recruits. (Reannouncement with New Availability Information) [R] . Struewing, J. P., Hyams, K. C., Tueller, J. E., 1993

机译：年轻人中麻疹，腮腺炎和水痘的风险：美国海军和海军陆战队新兵的血清学调查。（重新公布新的可用性信息）

A Third Dose of Measles-Mumps-Rubella Vaccine to Improve Immunity Against Mumps in Young Adults

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