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Nasopharyngeal carcinoma with mastoid recurrence after concurrent chemoradiotherapy masquerading as acute otomastoiditis

机译:鼻咽癌患有乳突复发后的乳突复发后伪装成急性耳垂性炎

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摘要

Nasopharyngeal cancer (NPC) with mastoid recurrence is extraordinarily rare, and its development is thought to involve the Eustachian tube. We herein report a case of NPC with mastoid recurrence masquerading as acute otomastoiditis with facial paralysis in a 60-year-old man 44 months after concurrent chemoradiotherapy. The diagnosis was confirmed by exploratory tympanomastoidectomy with biopsy and Epstein-Barr-encoding region (EBER) in situ hybridization. Distant liver metastasis was detected simultaneously, and the patient underwent salvage treatment. He died 15 months later. Despite the rarity of mastoid recurrence, clinicians should be vigilant in the differential diagnosis of mastoiditis in patients with NPC after radiotherapy. Tumor biopsy and EBER in situ hybridization can aid in the accurate diagnosis of this uncommon condition. (C) 2016 Elsevier B.V. All rights reserved.
机译:鼻咽癌(NPC)具有乳突复发的鼻咽癌非常罕见,其发展被认为涉及咽鼓管。 我们在此报告了患有乳突复发的NPC伪装成患有急性Otomastoiditis,在同时进行化学疗法后44个月的60岁男子中的面部瘫痪。 通过原位杂交的活组织检查和EBER-BART编码区域(EBER)通过探索性鼓膜术切除术进行诊断。 同时检测远处肝脏转移,患者接受挽救治疗。 他在15个月后去世了。 尽管乳突复发性罕见,但临床医生应在放射治疗后NPC患者的患者差异诊断中保持警惕。 肿瘤活组织检查和EBER原位杂交可以帮助准确诊断这种罕见的情况。 (c)2016年Elsevier B.v.保留所有权利。

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