Review of UK malaria treatment guidelines 2016 (Public Health England Advisory Committee on Malaria Prevention)

摘要

This guideline covers the diagnosis and management of malaria, and was published in the Journal of Infection in June 2016.1 It was written by the Public Health England Advisory Committee on Malaria Prevention (PHE ACMP) based on review of available evidence and expert consultation (using a modified Grading of Recommendations Assessment, Development and Evaluation criteria for assessment of evidence and strength of recommendation), to be in line with WHO guidelines on management of malaria.2 It relates to malaria in both adults and children in the UK although here we focus on the diagnosis and management of children returning to the UK with suspected malaria. Malaria is the most common imported tropical pathogen in the UK, and children comprise about 10% of the 1300-1800 UK cases per annum. Plas-modium falciparum is by far the most common (around 75% of cases) and is associated with more severe disease.