Copper Mediated Three-Component Reactions of Alkynes, Azides, and Propargylic Carbonates: Synthesis of 5-Allenyl-1,2,3-Triazoles

摘要

A copper-mediated one-pot sequential reaction of terminal alkynes, azides, and propargylic carbonates is reported. The three component reaction occurs readily at room temperature to afford a 5-allenyl-1,2,3-triazoles in high yields, providing a straightforward approach to 1,3,5-trisubstituted triazoles using easily available Cu(I) reagent.