Copper(I)-Catalyzed Alkyl- and Arylsulfenylation of 3,4-Dihalo-2(5H)-furanones (X= Br, Cl) with Sulfoxides under Mild Conditions

摘要

An efficient copper(I)/proline sodium salt-catalyzed alkyl-and arylsulfenylation of C(sp(2))-X 3,4-dihalo-2(5H)-furanone compounds with sulfoxides is described. For inexpensive C(sp(2))-Cl compounds, there is also a satisfactory reactivity with the moderate yields. This transformation provides a novel approach for the utilization of sulfoxides (not only DMSO) as sulfur source at mild temperatures without the need for an anaerobic atmosphere. More importantly, both sulfoxide and proline sodium salt can play a dual role in this reaction.