Trends in incidence of long-term-care facility onset Clostridium difficile infections in 10 US geographic locations during 2011-2015

摘要

During 2011-2015, the adjusted long-term-care facility onset Clostridium difficile infection incidence rate in persons aged = 65 years decreased annually by 17.45% (95% confidence interval, 14.53%-20.43%) across 10 US sites. A concomitant decline in inpatient fluoroquinolone use and the C difficile epidemic strain NAP1/027 among persons aged = 65 years may have contributed to the decrease in long-term-care facilityonset C difficile infection incidence rate. Published by Elsevier Inc. on behalf of Association for Professionals in Infection Control and Epidemiology, Inc.