Urine Fibrosis Markers and Risk of Allograft Failure in Kidney Transplant Recipients: A Case-Cohort Ancillary Study of the FAVORIT Trial

Ix Joachim H.; Katz Ronit; Bansal Nisha; Foster Meredith; Weiner Daniel E.; Tracy Russell; Jotwani Vasantha; Hughes-Austin Jan; Mckay Dianne; Gabbai Francis; Hsu Chi-yuan; Bostom Andrew; Levey Andrew S.; Shlipak Michael G.

首页> 外文期刊>American Journal of Kidney Diseases: The official journal of the National Kidney Foundation >Urine Fibrosis Markers and Risk of Allograft Failure in Kidney Transplant Recipients: A Case-Cohort Ancillary Study of the FAVORIT Trial

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Urine Fibrosis Markers and Risk of Allograft Failure in Kidney Transplant Recipients: A Case-Cohort Ancillary Study of the FAVORIT Trial

机译：肾移植受者的尿液纤维化标志物和同种异体移植失效的风险：FASTIT试验的案例 - 队列辅助研究

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Background: Kidney tubulointerstitial fibrosis marks risk for allograft failure in kidney transplant recipients, but is poorly captured by estimated glomerular filtration rate (eGFR) or urine albumin-creatinine ratio (ACR). Whether urinary markers of tubulointerstitial fibrosis can noninvasively identify risk for allograft failure above and beyond eGFR and ACR is unknown.

机译：背景：肾细胞间纤维化纤维化标志着肾移植受者的同种异体移植失败的风险，但通过估计的肾小球过滤速率（EGFR）或尿白蛋白 - 肌酐比（ACR）捕获不良。管拓纤维化的尿记录是否可以非侵染地识别同种异体移植失败的风险，而EGFR和ACR是未知的。

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来源
《American Journal of Kidney Diseases: The official journal of the National Kidney Foundation 》 |2017年第3期| 共10页
作者
Ix Joachim H.; Katz Ronit; Bansal Nisha; Foster Meredith; Weiner Daniel E.; Tracy Russell; Jotwani Vasantha; Hughes-Austin Jan; Mckay Dianne; Gabbai Francis; Hsu Chi-yuan; Bostom Andrew; Levey Andrew S.; Shlipak Michael G.;
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作者单位

Univ Calif San Diego Div Nephrol Hypertens Dept Med 3350 La Jolla Village Dr Mail Code 9111-H;

Univ Washington Div Nephrol Kidney Res Inst Seattle WA 98195 USA;

Tufts Med Ctr Div Nephrol Dept Med Boston MA USA;

Tufts Med Ctr Div Nephrol Dept Med Boston MA USA;

Univ Vermont Dept Pathol Burlington VT 05405 USA;

Univ Calif San Francisco Dept Med Div Nephrol San Francisco CA USA;

Univ Calif San Diego Dept Orthoped Surg 3350 La Jolla Village Dr Mail Code 9111-H San Diego CA;

Univ Calif San Diego Div Nephrol Hypertens Dept Med 3350 La Jolla Village Dr Mail Code 9111-H;

Univ Calif San Diego Div Nephrol Hypertens Dept Med 3350 La Jolla Village Dr Mail Code 9111-H;

Univ Calif San Francisco Dept Med Div Nephrol San Francisco CA USA;

Rhode Isl Hosp Providence RI USA;

Tufts Med Ctr Div Nephrol Dept Med Boston MA USA;

San Francisco Vet Affairs Hosp Gen Internal Med Sect San Francisco CA USA;

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原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病） ;
关键词
Fibrosis; kidney transplantation; allograft failure; risk factor; inflammation; biomarker; urinary marker; tubulo-interstitial fibrosis; alpha(l)-microglobulin (A1M); monocyte chemoattractant protein 1 (MCP-1); kidney transplant recipient (KTR); end-stage renal disease (ESRD); case-cohort;

机译：纤维化;肾移植;同种异体移植失败;危险因素;炎症;生物标志物;尿标记物;管状标记;α-间质纤维化;α（l）-microglobulin（A1m）;单核细胞化学蛋白1（MCP-1）;肾移植受体（KTR）;末期肾病（ESRD）;案例 - 队列;

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专利

1. Urine Fibrosis Markers and Risk of Allograft Failure in Kidney Transplant Recipients: A Case-Cohort Ancillary Study of the FAVORIT Trial [J] . Ix Joachim H., Katz Ronit, Bansal Nisha, American Journal of Kidney Diseases: The official journal of the National Kidney Foundation . 2017 ,第3期

机译：肾移植受者的尿液纤维化标志物和同种异体移植失效的风险：FASTIT试验的案例 - 队列辅助研究
2. Urinary Markers of Fibrosis and Risk of Cardiovascular Events and Death in Kidney Transplant Recipients: The FAVORIT FAVORIT Trial [J] . Park M., Katz R., Shlipak M. G., American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons . 2017 ,第10期

机译：肾移植受者的纤维化纤维化和心血管事件和死亡风险的尿记录：青睐偏爱审判
3. Blood Pressure, Chronic Kidney Disease Progression, and Kidney Allograft Failure in Kidney Transplant Recipients: A Secondary Analysis of the FAVORIT Trial [J] . Malhotra Rakesh, Katz Ronit, Weiner Daniel E., American Journal of Hypertension . 2019 ,第9期

机译：肾移植受者的血压，慢性肾疾病进展和肾同种异体移植失效：偏爱试验的二级分析
4. Glutathione transferase as markers for allograft rejection in liver and kidney transplantation [C] . Shigeki Tsuchida, Mamoru Sato, TakehikoYamazaki, Hirosaki Transplantation Research Project . 2000

机译：谷胱甘肽转移酶作为肝脏和肾移植在同种异体移植排斥反应的标志物
5. The effect of maintaining high hemoglobin levels on long-term kidney function in kidney transplant recipients: a randomized controlled trial [D] . Tsujita Makoto, 辻田誠 2019

机译：维持高血红蛋白水平对肾移植受者长期肾脏功能的影响：一项随机对照试验
6. Serum Phosphorus and Risk of Cardiovascular Disease All-Cause Mortality or Graft Failure in Kidney Transplant Recipients: An Ancillary Study of the FAVORIT Trial Cohort [O] . Basma Merhi, Theresa Shireman, Myra A. Carpenter, -1

机译：血清磷与肾脏移植受者心血管疾病全因死亡率或移植失败的风险：一项FAVORIT试验队列的辅助研究
7. Urine Fibrosis Markers and Risk of Allograft Failure in Kidney Transplant Recipients: A Case-Cohort Ancillary Study of the FAVORIT Trial [O] . Joachim H. Ix, Ronit Katz, Nisha Bansal, 2017

机译：肾移植受者的尿纤维化标记和同种异体移植衰竭的风险：FASTIT试验的案例 - 队列辅助研究
8. End-Stage Renal Disease: Characteristics of Kidney Transplant Recipients, Frequency of Transplant Failures, and Cost to Medicare [R] . 2007

机译：终末期肾病：肾移植受者的特征，移植失败的频率和医疗保险的成本

Urine Fibrosis Markers and Risk of Allograft Failure in Kidney Transplant Recipients: A Case-Cohort Ancillary Study of the FAVORIT Trial

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