Asymptomatic Soft Erythematous Dome-Shaped Papule on the Chest: Answer

摘要

ANSWERBenign epithelioid schwannoma.Further immunohistochemical studies revealed strong positivity for S100, NKI/C3, and vimentin. Some cells were positive for SOX 10. Importantly, collagen type IV was seen in a diffuse pericellular distribution and around small groups of cells (Fig. 1). Staining with EMA, HMB45, CD68, pankeratin, EMA, and GFAP demonstrated negative results. MIB-1 highlighted a low proliferative fraction (Fig. 2). The diagnosis of an epithelioid schwannoma was rendered.