Lineage Switch Between B-Lymphoblastic Leukemia and Acute Myeloid Leukemia Intermediated by 'Occult' Myelodysplastic Neoplasm Two Cases of Adult Patients With Evidence of Genomic Instability and Clonal Selection by Chemotherapy

摘要

Objectives: Lineage switch occurs in rare leukemias, and the mechanism is unclear. We report two cases of B-lymphoblastic leukemia (B-ALL) relapsed as acute myeloid leukemia (AML).