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A 3D Printed Implantable Device for Voiding the Bladder Using Shape Memory Alloy (SMA) Actuators

机译:一种用于使用形状记忆合金(SMA)执行器来排出膀胱的3D印刷植入装置

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Abstract >Underactive bladder or detrusor underactivity (DU) is defined as a reduction of contraction strength or duration of the bladder wall. Despite the serious healthcare implications of DU, there are limited solutions for affected individuals. A flexible 3D printed implantable device driven by shape memory alloys (SMA) actuators is presented here for the first time to physically contract the bladder to restore voluntary control of the bladder for individuals suffering from DU. This approach is used initially in benchtop experiments with a rubber balloon acting as a model for the rat bladder to verify its potential for voiding, and that the operating temperatures are safe for the eventual implantation of the device in a rat. The device is then implanted and tested on an anesthetized rat, and a voiding volume of more than 8% is successfully achieved for the SMA‐based device without any surgical intervention or drug injection to relax the external sphincter. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译:</span><Abstract XMLNS =“http://www.wiley.com/namespaces/wiley”type =“main”xml:lang =“en”> <标题类型=“main”>抽象</ title> >膀胱或排尿管不足(du)定义为膀胱壁的收缩强度或持续时间的降低。尽管对DU的医疗保健含义严重,但受影响的个人有限的解决方案。这是由形状记忆合金(SMA)致动器驱动的柔性3D印刷植入装置,首次在此处提供膀胱以恢复患有杜的个体的膀胱自愿控制以恢复膀胱的自愿控制。该方法最初在台上使用橡胶球囊中用作大鼠膀胱的模型,以验证其空隙的电位,并且操作温度对于在大鼠中的装置的最终植入中是安全的。然后将该装置植入并测试在麻醉的大鼠上,并且对于没有任何手术干预或药物注射的SMA的装置成功地实现了超过8%的空隙体积,以放宽外括约肌。</ p> </摘要> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-18063/'>《Advanced materials interfaces》</a> <b style="margin: 0 2px;">|</b><span>2017年第11期</span><b style="margin: 0 2px;">|</b><span>共1页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Hassani Faezeh Arab&option=202" target="_blank" rel="nofollow">Hassani Faezeh Arab;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Peh Wendy Yen Xian&option=202" target="_blank" rel="nofollow">Peh Wendy Yen Xian;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Gammad Gil Gerald Lasam&option=202" target="_blank" rel="nofollow">Gammad Gil Gerald Lasam;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Mogan Roshini Priya&option=202" target="_blank" rel="nofollow">Mogan Roshini Priya;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ng Tze Kiat&option=202" target="_blank" rel="nofollow">Ng Tze Kiat;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Kuo Tricia Li Chuen&option=202" target="_blank" rel="nofollow">Kuo Tricia Li Chuen;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ng Lay Guat&option=202" target="_blank" rel="nofollow">Ng Lay Guat;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Luu Percy&option=202" target="_blank" rel="nofollow">Luu Percy;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yen Shih‐Cheng&option=202" target="_blank" rel="nofollow">Yen Shih‐Cheng;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Lee Chengkuo&option=202" target="_blank" rel="nofollow">Lee Chengkuo;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of Electrical and Computer EngineeringNational University of Singapore4 Engineering Drive 3 #05‐45 Singapore 117583 Singapore;</p> <p>Singapore Institute for NeurotechnologyNational University of Singapore28 Medical Dr. #05‐COR Singapore 117456 Singapore;</p> <p>Singapore Institute for NeurotechnologyNational University of Singapore28 Medical Dr. #05‐COR Singapore 117456 Singapore;</p> <p>Singapore Institute for NeurotechnologyNational University of Singapore28 Medical Dr. #05‐COR Singapore 117456 Singapore;</p> <p>Raffles Hospital585 North Bridge Road Singapore 188770 Singapore;</p> <p>Singapore General HospitalOutram Road Singapore 169608 Singapore;</p> <p>Singapore General HospitalOutram Road Singapore 169608 Singapore;</p> <p>Singapore Institute for NeurotechnologyNational University of Singapore28 Medical Dr. #05‐COR Singapore 117456 Singapore;</p> <p>Department of Electrical and Computer EngineeringNational University of Singapore4 Engineering Drive 3 #05‐45 Singapore 117583 Singapore;</p> <p>Department of Electrical and Computer EngineeringNational University of Singapore4 Engineering Drive 3 #05‐45 Singapore 117583 Singapore;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/6960.html" title="特种结构材料">特种结构材料;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=3D printing&option=203" rel="nofollow">3D printing;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=actuators&option=203" rel="nofollow">actuators;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=flexible electronics&option=203" rel="nofollow">flexible electronics;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=shape memory alloy&option=203" rel="nofollow">shape memory alloy;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=under active bladder&option=203" rel="nofollow">under active bladder;</a> </p> <div class="translation"> 机译:3D打印;执行器;柔性电子;形状记忆合金;在活性膀胱下; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" 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href="/journal-cn-9920/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 航天器工程 </a> </span> <span> . 2016</span><span>,第003期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-33434_thesis/02022841781.html">应用于振动控制中的形状记忆合金弹簧的设计</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=C.LIANT&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 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<li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130423560158.html">SHAPE MEMORY ALLOY (SMA) ACTUATORS AND DEVICES INCLUDING BIO-INSPIRED SHAPE MEMORY ALLOY COMPOSITE (BISMAC) ACTUATORS</a> <b>[P]</b> . <span> 外国专利: <!-- 美国专利: --> US2012174571A1 </span> <span> . 2012-07-12</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:形状记忆合金(SMA)执行器和设备,包括生物启发的形状记忆合金复合(BISMAC)执行器 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130433852513.html">STRINGING METHOD OF SHAPE MEMORY ALLOY, MANUFACTURING METHOD OF SHAPE MEMORY ALLOY ACTUATOR, SHAPE MEMORY ALLOY ACTUATOR, AND MANUFACTURING DEVICE OF SHAPE MEMORY ALLOY ACTUATOR</a> <b>[P]</b> . <span> 外国专利: <!-- 日本专利: --> JP2008248881A </span> <span> . 2008-10-16</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:形状记忆合金的拉伸方法,形状记忆合金致动器的制造方法,形状记忆合金致动器以及形状记忆合金致动器的制造装置 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130428842377.html">METHOD FOR FORMING COILED SHAPE-MEMORY ALLOY, COILED SHAPE-MEMORY ALLOY, ACTUATOR, POWER-ASSISTED DEVICE, POWER-ASSISTED DEVICE FOR ELBOW, AND LINK ACTUATOR</a> <b>[P]</b> . <span> 外国专利: <!-- 日本专利: --> JP2010150657A </span> <span> . 2010-07-08</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译:形成形状记忆合金的方法,形状记忆合金,致动器,功率辅助设备,用于肘部的功率辅助设备和链接致动器 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon 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