Cost Effectiveness Analysis of Type-2 Antidiabetic Drugs in PKU Muhammadiyah Yogyakarta Hospital, Indonesia

摘要

Introduction Diabetes mellitus (DM) still becomes serious problem in the health perspective. The burden-related DM, particularly DM type 2, are increasing annually. We performed the cost-effectiveness analysis of type 2 DM therapy in PKU Muhammadiyah Yogyakarta hospital, Indonesia.Patients type 2 DM with or without complication were included in this study. The data were collected from hospital database and the cost effectiveness analysis were performed using health care perspective. ICER were calculated using Biguanide as the reference. The proportion of male and femalepopulation in this study was considered equal. Most of the patiens were at older age (>45 years old). Furthermore, the most expensive treatment for type 2 DM patients was the combination of Sulfonylurea-Biguanide-Inhibitor DPP-IV. Compared to Biguanide, Sulfonylurea, Long acting Insulin-Biguanide,and mixed insulin generated higher effectiveness in the type 2 DM patients without complication. Our study showed that Biguanide is the most favorable option for treating type 2 DM patients in the current setting.