A Flow Cytometry-Based Assay for Procoagulant Platelet Polyphosphate

Labberton Linda; Long Andy T.; Gendler Sandra J.; Snozek Christine L.; Stavrou Evi X.; Nickel Katrin F.; Maas Coen; Blankenberg Stefan; Hernandez James S.; Renne Thomas

首页> 外文期刊>Cytometry, Part B. Clinical cytometry: the journal of the International Society for Analytical Cytology >A Flow Cytometry-Based Assay for Procoagulant Platelet Polyphosphate

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A Flow Cytometry-Based Assay for Procoagulant Platelet Polyphosphate

机译：用于促凝血血小板多磷酸盐的基于流式细胞术的测定

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BackgroundPlatelet polyphosphate is an inorganic procoagulant polymer of orthophosphate units that is stored in dense granules and is released upon platelet activation. Here, we describe an assay to measure polyphosphate on the surface of procoagulant human platelets.

机译：背景普拉特·多磷酸盐是储存在致密颗粒中的正磷酸盐单元的无机探测聚合物，并在血小板活化时释放。这里，我们描述了测量在促凝血剂人血小板表面上的多磷酸盐的测定。

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来源
《Cytometry, Part B. Clinical cytometry: the journal of the International Society for Analytical Cytology》 |2018年第2期|共5页
作者
Labberton Linda; Long Andy T.; Gendler Sandra J.; Snozek Christine L.; Stavrou Evi X.; Nickel Katrin F.; Maas Coen; Blankenberg Stefan; Hernandez James S.; Renne Thomas;
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作者单位

Karolinska Inst Clin Chem Dept Mol Med &

Surg Stockholm Sweden;

Univ Med Ctr Hamburg Eppendorf Inst Clin Chem &

Lab Med Hamburg Germany;

Mayo Clin Arizona Coll Med Mayo Clin Dept Biochem &

Mol Biol Scottsdale AZ USA;

Mayo Clin Arizona Dept Lab Med &

Pathol Scottsdale AZ USA;

Case Western Reserve Univ Dept Med Div Hematol &

Oncol Cleveland OH 44106 USA;

Karolinska Inst Clin Chem Dept Mol Med &

Surg Stockholm Sweden;

Univ Med Ctr Utrecht Dept Clin Chem &

Haematol Utrecht Netherlands;

Univ Heart Ctr Hamburg Eppendorf Dept Gen &

Intervent Cardiol Hamburg Germany;

Mayo Clin Arizona Dept Lab Med &

Pathol Scottsdale AZ USA;

Karolinska Inst Clin Chem Dept Mol Med &

Surg Stockholm Sweden;

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原文格式 PDF
正文语种 eng
中图分类血液学检验;
关键词
platelets; biomarker; flow cytometry; polyphosphate;

机译：血小板;生物标志物;流式细胞术;多磷酸盐;
入库时间 2022-08-20 00:27:22

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专利

1. A Flow Cytometry-Based Assay for Procoagulant Platelet Polyphosphate [J] . Labberton Linda, Long Andy T., Gendler Sandra J., Cytometry, Part B. Clinical cytometry: the journal of the International Society for Analytical Cytology . 2018,第2期

机译：用于促凝血血小板多磷酸盐的基于流式细胞术的测定
2. The effect of P2Y12 inhibition on platelet activation assessed with aggregation- and flow cytometry-based assays [J] . Leunissen Tesse C., Wisman Peter Paul, van Holten Thijs C., Platelets . 2017,第6期

机译：P2Y12抑制对聚集和流式细胞术测定评估血小板活化的影响
3. Effects of platelet binding on whole blood flow cytometry assays of monocyte and neutrophil procoagulant activity. [J] . Barnard MR, Linden MD, Frelinger AL 3rd, Journal of thrombosis and haemostasis: JTH . 2005,第11期

机译：血小板结合对单核细胞和中性粒细胞促凝活性的全血流式细胞术测定的影响。
4. Measurement of the flow induced procoagulant properties of platelets in a mechanical heart valve using prothrombin acetylation [C] . Danny Bluestein, Azhar Siddiqui, Jolyon Jesty Bioengineering conference . 1999

机译：使用凝血酶原乙酰化作用测量机械性心脏瓣膜中血小板引起的血流促凝特性
5. Effects of fluid shear stress on platelets: alpha(IIb)beta(3) integrin signaling and procoagulant properties in the presence of platelet antagonists. [D] . Haga, Jason Hideyo. 2001

机译：流体剪切应力对血小板的影响：在存在血小板拮抗剂的情况下，α（IIb）β（3）整联蛋白信号传导和促凝特性。
6. Application of an optimized flow cytometry-based quantification of Platelet Activation (PACT): Monitoring platelet activation in platelet concentrates [O] . Cécile H. Kicken, Mark Roest, Yvonne M. C. Henskens, -1

机译：基于优化流式细胞术的血小板活化（PACT）定量的应用：监测血小板浓缩液中的血小板活化
7. A novel flow cytometry-based platelet aggregation assay [O] . de Cuyper Iris M., Meinders Marjolein, van de Vijver Edith, 2013

机译：基于流式细胞仪的新型血小板聚集测定

A Flow Cytometry-Based Assay for Procoagulant Platelet Polyphosphate

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