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Optimization of Drug Safety Profile in Inflammatory Bowel Disease Through a Personalized Approach

机译:通过个性化方法优化炎症性肠病的药物安全性曲线

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摘要

Treatment strategies and treatment options have changed considerably over the past decade for Inflammatory Bowel Disease (IBD). Alongside this shift in therapeutic options has come an opportunity to personalize treatment decisions based on individual patient profiles and preferences. One of the most important aspects of therapy in IBD is treatment related risk, and an opportunity exists to personalize therapy through optimization of drug safety profiles in individual patients. In this review we discuss the potential risks of therapy in IBD, opportunities to mitigate those risks, and a personalized approach to consider when using these agents in clinical practice.
机译:在过去十年中,治疗策略和治疗方案发生了很大的变化,用于炎症性肠病(IBD)。 除此之外,治疗选项的转变已经有机会根据个体患者概况和偏好来个性化治疗决策。 IBD治疗中最重要的一项是治疗相关风险,并且通过在个别患者中的药物安全型材优化的优化来个性化治疗。 在这篇综述中,我们讨论了IBD中的潜在风险,减轻了这些风险的机会,以及在临床实践中使用这些药剂时需要考虑的个性化方法。

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