Acetic acid functionalized ionic liquid systems: An efficient and recyclable catalyst for the regioselective ring opening of epoxides with NaN3

摘要

In the present study, an environmentally benign, efficient, and solvent-free procedure was developed for the synthesis of 1,2-azidoalcohols by the regioselective ring opening of some epoxides with sodium azide (NaN3) in the presence of an acetic acid functionalized imidazolium salt [Cmmim]BF4 or [Cmmim]Br as a green and Bronsted acidic ionic liquid (BAIL) catalyst under mild and neutral reaction conditions at 60 degrees C. The remarkable features of this procedure are excellent regioselectivity, simple work-up procedure, high yields of products, short reaction times, and ease of recyclability of ionic liquids. (C) 2016 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.