Graded functionalization of biomaterial surfaces using mussel-inspired adhesive coating of polydopamine

Sajeesh Kumar Madhurakkat Perikamana; Young Min Shin; Jin Kyu Lee; Yu Bin Lee; Yunhoe Heo; Taufiq Ahmad; So Yeon Park; Jisoo Shin; Kyung Min Park; Hyun Suk Jung; Seung-Woo Cho; Heungsoo Shin

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Graded functionalization of biomaterial surfaces using mussel-inspired adhesive coating of polydopamine

机译：使用贻贝鼓励粘合剂涂层的生物材料表面的渐变官能化

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?A method for generating polydopamine (PD) gradient on biomaterial has been reported.

?PD gradient substrates showed gradient in surface chemistry and hydrophilicity.

?PD gradient substrates were able to modulate the spatial distribution of biomolecules.

Abstract

Biomaterials with graded functionality have various applications in cell and tissue engineering. In this study, by controlling oxidative polymerization of dopamine, we demonstrated universal techniques for generating chemical gradients on various materials with adaptability for secondary molecule immobilization. Diffusion-controlled oxygen supply was successfully exploited for coating of polydopamine (PD) in

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？已经报道了一种在生物材料上产生多氨胺（Pd）梯度的方法。

？ PD梯度基板在表面化学中显示梯度stry和亲水性。

？ PD梯度基板能够调制生物分子的空间分布。 Abstract

具有分级功能的生物材料在细胞和组织工程中具有各种应用。在该研究中，通过控制多巴胺的氧化聚合，我们证明了用于在各种材料上产生化学梯度的通用技术，适应二次分子固定。扩散控制的氧气供应被成功利用用于涂覆多薯类（PD）

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来源
《Colloids and Surfaces, B. Biointerfaces》 |2017年第2017期|共11页
作者
Sajeesh Kumar Madhurakkat Perikamana; Young Min Shin; Jin Kyu Lee; Yu Bin Lee; Yunhoe Heo; Taufiq Ahmad; So Yeon Park; Jisoo Shin; Kyung Min Park; Hyun Suk Jung; Seung-Woo Cho; Heungsoo Shin;
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作者单位

Department of Bioengineering Hanyang University;

Department of Bioengineering Hanyang University;

Department of Bioengineering Hanyang University;

Department of Bioengineering Hanyang University;

Department of Bioengineering Hanyang University;

Department of Bioengineering Hanyang University;

School of Advanced Materials Science &

Engineering Sungkyunkwan University;

Department of Biotechnology Yonsei University;

Division of Bioengineering College of Life Sciences and Bioengineering Incheon National University;

School of Advanced Materials Science &

Engineering Sungkyunkwan University;

Department of Biotechnology Yonsei University;

Department of Bioengineering Hanyang University;

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正文语种 eng
中图分类胶体化学（分散体系的物理化学）;
关键词
Gradient systems; Tissue engineering; Chemical modification; Polydopamine; Biomolecule gradient;

机译：梯度系统;组织工程;化学改性;聚二胺;生物分子梯度;

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专利

1. Graded functionalization of biomaterial surfaces using mussel-inspired adhesive coating of polydopamine [J] . Sajeesh Kumar Madhurakkat Perikamana, Young Min Shin, Jin Kyu Lee, Colloids and Surfaces, B. Biointerfaces . 2017,第期

机译：使用贻贝鼓励粘合剂涂层的生物材料表面的渐变官能化
2. Enhancement of growth and osteogenic differentiation of MC3T3-E1 cells via facile surface functionalization of polylactide membrane with chitooligosaccharide based on polydopamine adhesive coating [J] . Li Huihua, Luo Chuang, Luo Binghong, Applied Surface Science . 2016,第jana1ptaB期

机译：通过基于聚多巴胺粘合剂涂层的壳寡糖对丙交酯膜进行易表面功能化，促进MC3T3-E1细胞的生长和成骨分化
3. Mussel-Inspired One-Step Fabrication of Ultralow-Friction Coatings on Diverse Biomaterial Surfaces [J] . Wei Qiangbing, Liu Xiaoqian, Yue Qinyu, Langmuir: The ACS Journal of Surfaces and Colloids . 2019,第24期

机译：贻贝鼓励在多种生物材料表面上的超级摩擦涂层的一步制造
4. Design of Biofunctional Platforms: Differently Processed Biomaterials with Polydopamine Coating [C] . Simona Zuppolini, Iriczalli Cruz-Maya, Vincenzo Guarino, Italian National Association on Sensors and Microsystems Regional Workshop . 2020

机译：生物功能平台的设计：用聚二胺涂层不同加工生物材料
5. Mussel Adhesive-Inspired Surface Modification to Design Bi-Functional Antibacterial Coatings [D] . Alves, Diana Filipa Barros 2016

机译：贻贝胶粘剂启发的表面改性，以设计双功能抗菌涂料
6. Preparation of Stable Superhydrophobic Coatings on Wood Substrate Surfaces via Mussel-Inspired Polydopamine and Electroless Deposition Methods [O] . Kaili Wang, Youming Dong, Wei Zhang, 2017

机译：贻贝启发式聚多巴胺和化学沉积方法在木材基材表面制备稳定的超疏水涂层
7. Preparation of Stable Superhydrophobic Coatings on Wood Substrate Surfaces via Mussel-Inspired Polydopamine and Electroless Deposition Methods [O] . Kaili Wang, Youming Dong, Wei Zhang, 2017

机译：用贻贝激发的聚多巴胺和化学沉积法制备木质基材表面稳定的超疏水涂层
8. Surface Crack Problem for a Functionally Graded Coating Bonded to a Homogeneous Layer [R] . Erdogan, F. , Kasmaklar, M. 2000

机译：功能梯度涂层与均匀层结合的表面裂纹问题

Graded functionalization of biomaterial surfaces using mussel-inspired adhesive coating of polydopamine

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