Combined Ischemic Preconditioning and Resveratrol Improved Blood-brain Barrier Breakdown via Hippo/YAP/TAZ Signaling Pathway

摘要

Background: Transient Ischemia/Reperfusion (I/R) is the main reason for brain injury and results in disruption of the Blood-Brain Barrier (BBB). It had been reported that BBB injury is one of the main risk factors for early death in patients with cerebral ischemia. Numerous investigations focus on the study of BBB injury which have been carried out.