Impact of Adjuvant Anthracycline-Based and Taxane-Based Chemotherapy on Plasma VEGF Levels and Cognitive Function in Breast Cancer Patients: A Longitudinal Study

Ng Terence; Phey Xiang Yun; Yeo Hui Ling; Shwe Maung; Gan Yan Xiang; Ng Raymond; Ho Han Kiat; Chan Alexandre

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Impact of Adjuvant Anthracycline-Based and Taxane-Based Chemotherapy on Plasma VEGF Levels and Cognitive Function in Breast Cancer Patients: A Longitudinal Study

机译：基于辅助蒽环类和紫杉烷基化疗对乳腺癌患者血浆VEGF水平和认知功能的影响：纵向研究

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摘要

Vascular endothelial growth factor (VEGF) levels increase after initiation of anthracycline therapy and decrease after initiation of taxane therapy in breast cancer patients. VEGF was not associated with cognitive changes in patients receiving chemotherapy.

机译：血管内皮生长因子（VEGF）水平在发起蒽环素治疗后增加，并在乳腺癌患者中发酵紫杉烷治疗后降低。 VEGF与接受化疗患者的认知变化没有与接受化疗的关系无关。

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《Clinical breast cancer》 |2018年第5期|共11页
作者
Ng Terence; Phey Xiang Yun; Yeo Hui Ling; Shwe Maung; Gan Yan Xiang; Ng Raymond; Ho Han Kiat; Chan Alexandre;
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作者单位

Natl Univ Singapore Dept Pharm Blk S4A Level 3 18 Sci Dr 4 Singapore 117543 Singapore;

Natl Univ Singapore Dept Pharm Blk S4A Level 3 18 Sci Dr 4 Singapore 117543 Singapore;

Natl Univ Singapore Dept Pharm Blk S4A Level 3 18 Sci Dr 4 Singapore 117543 Singapore;

Natl Univ Singapore Dept Pharm Blk S4A Level 3 18 Sci Dr 4 Singapore 117543 Singapore;

Natl Univ Singapore Dept Pharm Blk S4A Level 3 18 Sci Dr 4 Singapore 117543 Singapore;

Natl Canc Ctr Singapore Div Med Oncol Singapore Singapore;

Natl Univ Singapore Dept Pharm Blk S4A Level 3 18 Sci Dr 4 Singapore 117543 Singapore;

Natl Univ Singapore Dept Pharm Blk S4A Level 3 18 Sci Dr 4 Singapore 117543 Singapore;

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正文语种 eng
中图分类肿瘤学;
关键词
Chemobrain; Cognition; Neuropsychology; Vascular endothelial growth factor;

机译：Chemobrain;认知;神经心理学;血管内皮生长因子;

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专利

1. 每周一次的紫杉烷–蒽环类联合方案与3周一次的以蒽环类为基础方案治疗r局部晚期乳腺癌的随机对照研究 [J] . Qiu-Wen Tan, Ting Luo, Hong Zheng, 癌症（英文版） . 2018,第002期
2. Impact of Adjuvant Anthracycline-Based and Taxane-Based Chemotherapy on Plasma VEGF Levels and Cognitive Function in Breast Cancer Patients: A Longitudinal Study [J] . Ng Terence, Phey Xiang Yun, Yeo Hui Ling, Clinical breast cancer . 2018,第5期

机译：基于辅助蒽环类和紫杉烷基化疗对乳腺癌患者血浆VEGF水平和认知功能的影响：纵向研究
3. Anti-Müllerian hormone (AMH) levels in premenopausal breast cancer patients treated with taxane-based adjuvant chemotherapy – A translational research project of the SUCCESS A study [J] . Elisabeth Trapp, J. Steidl, B. Rack, The Breast : . 2017,第期

机译：抗Müllerian激素（AMH）患有基于紫杉烷的辅助化疗治疗的前辈乳腺癌患者 - 这是一项研究的翻译研究项目
4. Cognitive function of older patients receiving adjuvant chemotherapy for breast cancer: a pilot prospective longitudinal study. [J] . Hurria A, Rosen C, Hudis C, Journal of the American Geriatrics Society . 2006,第6期

机译：接受乳腺癌辅助化疗的老年患者的认知功能：一项前瞻性前瞻性纵向研究。
5. Clinical implications of HER-2 and p53 in taxane-based and anthracycline-based neoadjuvant chemotherapy in breast cancer [C] . World congress on breast diseases . 2008

机译：HER-2和P53在紫杉烷基和蒽环类新辅助化疗的乳腺癌中的临床意义
6. The Effects of Adjuvant Chemotherapy on Brain Function in Breast Cancer Patients and a Cancer-Chemotherapy Rodent Model. [D] . Barr, Alicia Thomas. 2014

机译：辅助化疗对乳腺癌患者脑功能的影响和癌症化学疗法的啮齿动物模型。
7. Extracellular Vesicle Proteome of Breast Cancer Patients with and Without Cognitive Impairment Following Anthracycline-based Chemotherapy: An Exploratory Study [O] . Yong Qin Koh, Ding Quan Ng, Chiu Chin Ng, 2021

机译：基于蒽环类化疗后的乳腺癌患者乳腺癌患者的细胞外囊肿蛋白质：探索性研究
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Impact of Adjuvant Anthracycline-Based and Taxane-Based Chemotherapy on Plasma VEGF Levels and Cognitive Function in Breast Cancer Patients: A Longitudinal Study

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