Palladium-Catalyzed Carbonylative Synthesis of 3-Methyleneisoindolin-1-ones from Ketimines with Hexacarbonylmolybdenum(0) as the Carbon Monoxide Source

摘要

An interesting procedure for the palladium-catalyzed carbonylative synthesis of 3-methyleneisoindolin-1-ones from ketimines was established. By using Mo(CO) 6 (0.3 equiv.) as the solid CO source and through C(sp(2))@H bond activation, the desired 3-methyleneisoindolin-1-ones were isolated in moderate to good yields.