Spotlight on Glycolysis: A New Target for Cord Blood Expansion

Andrea M. Patterson; Louis M. Pelus

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Spotlight on Glycolysis: A New Target for Cord Blood Expansion

机译：聚焦糖酵解：脐带血膨胀的新目标

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Umbilical cord blood (UCB) is a highly valuable but low-quantity source of hematopoietic stem cells (HSCs) for life-saving transplantations. Recently inNature Medicine, found that antagonism of a glycolysis-blocking pathway enhancesex?vivoexpansion of long-term HSCs from human UCB.

机译：脐带血（UCB）是一种高价值但低量的造血干细胞源（HSCs），用于挽救生命的移植。最近的纯药，发现糖酵解阻断途径的拮抗作用，来自人UCB的长期HSCs的vivoxpansion。

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《Cell stem cell》 |2018年第6期|共2页
作者
Andrea M. Patterson; Louis M. Pelus;
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Department of Microbiology and Immunology Indiana University School of Medicine;

Department of Microbiology and Immunology Indiana University School of Medicine;

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原文格式 PDF
正文语种 eng
中图分类细胞生物学;
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1. Spotlight on Glycolysis: A New Target for Cord Blood Expansion [J] . Andrea M. Patterson, Louis M. Pelus Cell stem cell . 2018,第6期

机译：聚焦糖酵解：脐带血膨胀的新目标
2. Ex-Vivo Expansion of Previously Cryopreserved, Thawed and Re-Cryopreserved Cord Blood Mononuclear Cells (CBMC) Utilizing K562-mbIL21-41BBL; Potential for Adoptive Cellular Immunotherapy Post Umbilical Cord Blood Transplantation (UCBT) [J] . Flower Allyson, Chu Yaya, Ayello Janet, Biology of blood and marrow transplantation: journal of the American Society for Blood and Marrow Transplantation . 2016,第3Suppla1期

机译：使用K562-mbIL21-41BBL的先前冷冻保存，解冻和重新冷冻保存的脐血单核细胞（CBMC）的体外扩增;脐带血移植（UCBT）后采用过继细胞免疫疗法的潜力
3. Ex Vivo Expansion of Hematopoietic Stem- and Progenitor Cells from Cord Blood in Coculture with Mesenchymal Stroma Cells from Amnion, Chorion, Wharton's Jelly,Amniotic Fluid, Cord Blood, and Bone Marrow [J] . Caroline Klein, Julian Strobel, Jurgen Zingsem, Tissue engineering, Part A . 2014,第23a24期

机译：与羊膜，绒毛膜，沃顿氏胶，羊水，脐带血和骨髓的间充质基质细胞共培养时，脐带血造血干细胞和祖细胞的体外扩增
4. SCALED-UP EXPANSION OF EQUINE CORD BLOOD MESENCHYMAL STEM CELLS (MSCS) FROM 10ML STIRRED SUSPENSION BIOREACTORS TO 100ML COMPUTER CONTROLLED STIRRED SUSPENSION BIOREACTORS USING COMPUTATIONAL FLUID DYNAMIC MODELING [C] . Erin Roberts, Tylor Walsh, Thomas G. Koch, Scale-up and manufacturing of cell-based therapies V . 2017

机译：利用计算流体动力学模型从10ML搅拌悬浮生物反应器到100ML计算机控制的搅拌悬浮生物反应器，将马鞭草血液间充质干细胞（MSCS）扩大规模
5. Ex vivo expansion of umbilical cord blood CD34+ subset hematopoietic stem cells on the covalently immobilized glycosaminoglycan/chitosan membrane surfaces. [D] . Lee, Jae Sam. 2006

机译：脐带血CD34 +亚型造血干细胞在共价固定的糖胺聚糖/壳聚糖膜表面的离体扩增。
6. The effect of amniotic membrane extract on umbilical cord blood mesenchymal stem cell expansion: is there any need to save the amniotic membrane besides the umbilical cord blood? [O] . Zahra Vojdani, Ali Babaei, Attiyeh Vasaghi, 2016

机译：羊膜提取物对脐带血间充质干细胞扩增的影响：除脐带血外是否还需要保存羊膜？
7. Spotlight on Glycolysis: A New Target for Cord Blood Expansion [O] . Andrea M. Patterson, Louis M. Pelus 2018

机译：聚焦糖酵解：脐带血膨胀的新目标

Spotlight on Glycolysis: A New Target for Cord Blood Expansion

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