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Racial differences in maternal and umbilical cord blood leukocyte telomere length and their correlations

机译:母体和脐带血白细胞端粒长度的种族差异及其相关性

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摘要

Telomere length at birth sets the baseline for telomere shortening and may influence adult disease risk like cancer. Telomere length is heritable, but may also be a marker of exposures in utero, including those influencing racial differences in risk. We examined racial differences in telomere length in maternal and umbilical cord blood from male neonates, and maternal-neonate correlations to generate hypotheses.
机译:出生时的端粒长度设定了端粒缩短的基线,可能影响癌症等成人疾病风险。 端粒长度是遗传的,但也可能是子宫内暴露的标志物,包括影响风险种族差异的人。 我们研究了来自男性新生儿的母亲和脐带血的端粒长度的种族差异,以及产生假设的母体新生儿相关性。

著录项

  • 来源
    《Cancer causes and control: CCC》 |2018年第8期|共9页
  • 作者单位

    Johns Hopkins Bloomberg Sch Publ Hlth Dept Epidemiol 615 N Wolfe St Baltimore MD 21205 USA;

    Johns Hopkins Univ Sch Med Dept Pathol 600 N Wolfe St Baltimore MD 21287 USA;

    Johns Hopkins Bloomberg Sch Publ Hlth Dept Epidemiol 615 N Wolfe St Baltimore MD 21205 USA;

    Johns Hopkins Bloomberg Sch Publ Hlth Dept Epidemiol 615 N Wolfe St Baltimore MD 21205 USA;

    Univ Zurich Div Chron Dis Epidemiol Epidemiol Biostat &

    Prevent Inst Hirschengraben 84 CH-8001;

    Johns Hopkins Univ Sch Med Dept Gynecol &

    Obstet 600 N Wolfe St Baltimore MD 21287 USA;

    NCI Div Canc Control &

    Populat Sci 9609 Med Ctr Dr Bethesda MD 20892 USA;

    Johns Hopkins Univ Sch Med Dept Pathol 600 N Wolfe St Baltimore MD 21287 USA;

    Johns Hopkins Bloomberg Sch Publ Hlth Dept Epidemiol 615 N Wolfe St Baltimore MD 21205 USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 肿瘤学;
  • 关键词

    Telomeres; Cord blood; Race; Maternal;

    机译:端粒;脐带血;种族;母亲;

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