Considerable improvement in survival for patients aged 60-84 years with high grade malignant gliomas-Data from the Swedish Brain Tumour Population-based Registry

摘要

We analysed data reported from the regions with the most active registration during the period 1999— 2009, and the patient coverage was between 94% and 100%. It was calculated as the percentage of diagnoses in the Swedish National Brain Tumour Registry of corresponding diagnoses recorded in the Swedish Cancer Registry during the same period,, and included 1844 patients, of which 1037 patients were 60-84 years of age and 587 patients 60-69 years of age. Survival data for patients 60—84 years of age with high grade malignant gliomas, i.e. glio-blastoma (WHO grade IV), anaplastic astrocytoma (WHO grade III) and anaplastic oligodendroglial tumours (grade III), was collected from three health care regions with the most active registration in Sweden; the Northern region, the Uppsala region and the South-east region. The choice of these specific regions was governed only by registration activity, and we have no reasons to assume that this population differs from the rest of the Swedish patient population. The included regions represented 45% of the population in Sweden as in 2007. By delimiting the diagnoses to a maximum of 84 years of age, less of the diagnoses should be diluted by patients with extremely poor prognosis irrespective of treatment.