Efficacy, safety and pharmacokinetics of sugammadex 4 mg kg(-1) for reversal of deep neuromuscular blockade in patients with severe renal impairment

摘要

Background: This study evaluated efficacy and safety of sugammadex 4 mg kg(-1) for deep neuromuscular blockade (NMB) reversal in patients with severe renal impairment (creatinine clearance [CLCR] <30 ml min(-1)) us those with normal renal function (CLCR >= 80 ml min(-1)).