Case of the month: Gastric wall thickening in association with hypereosinophilic syndrome.

摘要

A 71-year-old woman with a background of quiescent rheumatoid arthritis was found to have an eosinophilia on routine blood tests by her general practitioner. She also suffered from occasional episodes of tongue swelling, but no specific allergens had been identified. She was referred to the haematology department and, after further investigations, including bone marrow aspiration and trephine and peripheral blood DNA analysis, was diagnosed with hypereosinophilic syndrome (HES) associated with a small T cell receptor gene re-arranged clone. She also underwent a CT scan (Figure 1). Subsequently, an oesophago-gastro-duodenoscopy (OGD) showed a small mucosal ulcer and changes of benign erosive gastritis. No specific treatment was initiated for HES; however, she was commenced on a proton pump inhibitor (PPI).