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机译:研究

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Preoperative opioid use and complications X-ref Multiple studies have been published evaluating the effect of preoperative opioid use and postoperative outcomes. It will come as no surprise to any reader of 360, given the North American opioid crisis and the subsequent column inches in all journals given up to this dramatic problem, that research has now turned not only to quantifying the problem, but ascertaining what the potential risks in the surgical patient are. The majority of these previous investigations have defined preoperative use as any opioid consumption within one year prior to surgery, which is unlikely to be appropriate to drawing rigorous conclusions. Furthermore, there is as yet no evidence correlating the number and duration of opioids used and potential postoperative complications. To clarify this tumultuous situation, a group from Columbus, Ohio (USA) has investigated preoperative opiate use prior to large joint arthro-plasty and lumbar fusion and correlated it to postoperative complications.1 This group used national insurance claims data between 2007 and 2015 to identify their cohort of 58 082 primary total knee arthroplasties (TKAs), total hip arthroplasties (THAs), and single- or two-level posterior lumbar fusions (PLFs) carried out to treat spondylosis. The group then divided preoperative opioid use into three categories (naive, three months or less, three to six months, more than six months but stopped three months before surgery, and more than six months of continuous use) and, by using these categorized outcomes, set out to establish if there was a link between opioid use and duration with adverse surgical outcomes.
机译:术前阿片类药物使用和并发症X-ref多项研究已经公布了评估术前阿片类药物和术后结果的影响。鉴于北美阿片类药物危机和所有期刊的众所周知,鉴于这一戏剧性问题的所有期刊中的任何读者,这一点毫不奇怪,这研究现在不仅转化了量化的问题,而且确定了什么潜力手术患者的风险是。这些以前的大部分研究已经定义了在手术前一年内作为任何阿片类药物的术前用途,这不太可能适合吸引严格的结论。此外,还没有证据表明使用的阿片类药物的数量和持续时间和潜在的术后并发症。为了澄清这种动荡的情况,来自哥伦布,俄亥俄州(美国)的一群群体在大关节 - 塑料和腰椎融合之前研究了术前阿片类药物,并将其与术后并发症相关联。识别其队列的58 082初级总膝关节缩窄症(TKAS),总髋关节关节塑料(THA)和单级或两级后腰椎融合(PLF),用于治疗脊柱型。该组然后将术前阿片类药物分为三类(天真,三个月或更少,三到六个月,六个月以上,手术前三个月停止,持续六个月的连续使用),并通过使用这些分类的结果,首先建立阿片类药物在使用和持续时间之间的链接,具有不良外科结果。

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