Qingjie Fuzheng Granule attenuates 5-fluorouracil-induced intestinal mucosal damage

Zhang Ling; Jin Yiyi; Peng Jun; Chen Wujin; Lu Lisha; Lin Jiumao

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Qingjie Fuzheng Granule attenuates 5-fluorouracil-induced intestinal mucosal damage

机译：Qing截F U正granule attenuates 5-法罗人哦uracil-induced intestinal mucosal damage

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摘要

Objective: 5-Fluorouracil (5-FU)-based chemotherapy often causes several drawbacks including weight loss, diarrhea, myelosuppression, and the intestinal mucositis. This study aimed to evaluate the protective effect of Qingjie Fuzheng Granule (QFG) on 5-FU-induced intestinal mucositis in CT-26 tumor-bearing xenograft mice and investigated the possible molecular mechanism.

机译：目的：5-氟尿嘧啶（5-FU）的化疗常常导致几种缺点，包括减肥，腹泻，髓抑制和肠粘膜炎。本研究旨在评估青捷富正颗粒（QFG）对5富诱导的肠粘膜肌肌小鼠5-Fu诱导的肠粘膜炎的保护作用，并研究了可能的分子机制。

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来源
《Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie》 |2019年第118期|共9页
作者
Zhang Ling; Jin Yiyi; Peng Jun; Chen Wujin; Lu Lisha; Lin Jiumao;
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作者单位

Fujian Univ Tradit Chinese Med Acad Integrat Med Fuzhou 350122 Fujian Peoples R China;

Fujian Univ Tradit Chinese Med Acad Integrat Med Fuzhou 350122 Fujian Peoples R China;

Fujian Univ Tradit Chinese Med Acad Integrat Med Fuzhou 350122 Fujian Peoples R China;

Fujian Univ Tradit Chinese Med Oncol Dept Affiliated Peoples Hosp Fuzhou 350004 Fujian Peoples;

Fujian Univ Tradit Chinese Med Oncol Dept Affiliated Peoples Hosp Fuzhou 350004 Fujian Peoples;

Fujian Univ Tradit Chinese Med Acad Integrat Med Fuzhou 350122 Fujian Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
Qingjie Fuzheng Granule; 5-fluorouracil; Intestinal mucosal damage; Inflammation; Apoptosis; Proliferation;

机译：富正颗粒;5-氟尿嘧啶;肠粘膜损伤;炎症;细胞凋亡;增殖;

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1. Dahuang Fuzi decoction reduces inflammation levels and alleviates intestinal mucosal barrier damage in septic rats [J] . Fusheng Liu, Chunyue Yu, Jin Liu, 中医科学杂志（英文） . 2020,第001期
2. Dahuang Fuzi decoction reduces inflammation levels and alleviates intestinal mucosal barrier damage in septic rats [J] . Fusheng Liu, Chunyue Yu, Jin Liu, 中医科学杂志(英文) . 2020,第001期
3. Qingjie Fuzheng Granule attenuates 5-fluorouracil-induced intestinal mucosal damage [J] . Zhang Ling, Jin Yiyi, Peng Jun, Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie . 2019,第118期

机译：Qing截F U正granule attenuates 5-法罗人哦uracil-induced intestinal mucosal damage
4. Protective Effects of Enteral Nutrition Supplemented with Crassostrea hongkongensis Polysaccharides Against 5-Fluorouracil-Induced Intestinal Mucosal Damage in Rats [J] . Cai Bingna, Wan Peng, Sun Huili, Journal of medicinal food . 2018,第4期

机译：肠内营养的保护作用补充了鲫鱼红松肌糖对大鼠5-氟尿嘧啶诱导的肠粘膜损伤
5. Histological and Ultra Structural Study of 5-fluorouracil-induced Small Intestinal Mucosal Damage in Rats [J] . S.A. Abou-Elez Gawish, D.A. Nosseir, N.M. Omar, Asian Journal of cell biology . 2013,第1期

机译：5-氟尿嘧啶致大鼠小肠黏膜损伤的组织学和超微结构研究
6. RESEARCH ABOUT AMBIENT TEMPERATURE CHANGE INDUC DAMAGE OF SMALL INTESTINAL MUCOSAL IMMUNIZATION BARRIER IN RAT [C] . Fanggeng Wu, Qingxian Zhu, Guozhu Hu, The 13th International congress for stereology . 2011

机译：大鼠小肠粘膜免疫屏障环境温度变化诱发损伤的研究
7. Effects of Prebiotic fibre Diets on Rat Mucosal Intestinal and Systemic Immunity and in Vitro Mechanistic Analysis of Anti-Inflammatory Effects of Lactobacillus Strains on Rat and Human Intestinal Epithelial Cells. [D] . McCarville, Justin. 2012

机译：益生元纤维饮食对大鼠粘膜肠和全身免疫的影响以及乳酸菌对大鼠和人肠上皮细胞抗炎作用的体外机理分析。
8. Remote ischemic preconditioning attenuates intestinal mucosal damage: insight from a rat model of ischemia–reperfusion injury [O] . Lars Hummitzsch, Karina Zitta, Rouven Berndt, 2019

机译：远程缺血预处理可减轻肠道粘膜损伤：从大鼠缺血再灌注损伤模型中获得的见解
9. Remote ischemic preconditioning attenuates intestinal mucosal damage: insight from a rat model of ischemia–reperfusion injury [O] . Lars Hummitzsch, Karina Zitta, Rouven Berndt, 2019

机译：远程缺血预处理衰减肠粘膜损伤：缺血再灌注损伤大鼠模型的洞察力

Qingjie Fuzheng Granule attenuates 5-fluorouracil-induced intestinal mucosal damage

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