Hepatic angiosarcoma (HAS) is a rare neoplasm, ac counting for only about 2% of all malignant hepatic tumors. Cytologic diagnosis of HAS has always been challenging for pathologists, and the neoplasm has been frequently diagnosed mistakenly as cholan-giocarcinoma or metastatic carcinoma due to nonspe cific cytopathologic features. In such cases, diagno sis of malignancy is straightforward because of obvious malignant cytopathologic features. However, immunocytochemistry is necessary to render a defini tive diagnosis. Epithelioid angisarcoma (EAS) is a rare subtype of angiosarcoma, and only 18 reported cases exist in the literature describing the cytologic features of this tumor.
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