A bacterial 2[4Fe-4S] ferredoxin as redox partner of the plastidic-type ferredoxin-NADP(+) reductase from Leptospira interrogans

摘要

Background: Ferredoxins are small iron-sulfur proteins that participate as electron donors in various metabolic pathways. They are recognized substrates of ferredoxin-NADP reductases (FNR) in redox metabolisms in mitochondria, plastids, and bacteria. We previously found a plastidic-type FNR in Leptospira interrogans (LepFNR), a parasitic bacterium of animals and humans. Nevertheless, we did not identify plant-type ferredoxins or fiavodoxins, the common partners of this kind of FNR.