Profiling of isomer-specific IgG N-glycosylation in cohort of Chinese colorectal cancer patients

摘要

Backgroud: Given the increasing morbidity and mortality of colorectal cancer (CRC), it is urgent to develop a noninvasive screening strategy for early diagnosis of CRC. Altered IgG glycosylation is associated with CRC progression, whereas the association of IgG isomeric glycosylation with CRC were not investigated.