A facile access to cis-dihydrofurobenzofuran from 2-(2,5-dihydro-furan-2-yl)-phenol

摘要

A facile access to cis-dihydrofurobenzofuran from a Pd-catalyzed intramolecular oxidative C-O bond formation of 2-(2,5-dihydrofuran-2-yl)- phenol is reported. The combined use of Pd(OAc)(2) as catalyst, acetonitrile as solvent and AgOAc or air as oxidant affords cis-dihydrofurobenzofurans in good (up to 83%) yields.