Investigation of the preventive effect of Sijunzi decoction on mitomycin C-induced immunotoxicity in rats by H-1 NMR and MS-based untargeted metabolomic analysis

摘要

Ethnopharmacological relevance: Sijunzi decoction (SJZD) is a well known traditional Chinese prescription used for the treatment of gastrointestinal disorders and immunity enhancement. It has been found to indeed improve life quality of chemotherapy patients and extensive used in clinical conbined with chemotherapeutics for the treatment of cancer.