Diarylheptanoid, a constituent isolated from methanol extract of Alpinia officinarum attenuates TNF-alpha level in Freund's complete adjuvant-induced arthritis in rats

Honmore Varsha S.; Kandhare Amit D.; Kadam Parag P.; Khedkar Vijay M.; Natu Arun D.; Rojatkar Supada R.; Bodhankar Subhash L.

首页> 外文期刊>Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs >Diarylheptanoid, a constituent isolated from methanol extract of Alpinia officinarum attenuates TNF-alpha level in Freund's complete adjuvant-induced arthritis in rats

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Diarylheptanoid, a constituent isolated from methanol extract of Alpinia officinarum attenuates TNF-alpha level in Freund's complete adjuvant-induced arthritis in rats

机译：二芳基肽，从甲醇提取物中分离的alpinia Officinarum的组成部分衰减弗氏完全佐剂诱导的关节炎的TNF-α水平

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Ethnopharmacological relevance: Rheumatoid arthritis (RA) is a chronic inflammatory and destructive joint disease that affects the worldwide population. Alpinia officinarum Hance (Zingiberaceae), rhizomes are widely used ethnobotanically as an anti-inflammatory, analgesic, and antioxidant agent in traditional medicine.

机译：民族科医药相关性：类风湿性关节炎（RA）是一种影响全球人口的慢性炎症和破坏性联合疾病。 alpinia Officinarum Hance（Zingiberaceae），根茎广泛用在传统医学中作为抗炎，镇痛药和抗氧化剂被广泛使用。

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《Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs 》 |2019年第2019期| 共13页
作者
Honmore Varsha S.; Kandhare Amit D.; Kadam Parag P.; Khedkar Vijay M.; Natu Arun D.; Rojatkar Supada R.; Bodhankar Subhash L.;
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作者单位

MES Abasaheb Garware Coll Dept Chem Post Grad &

Res Ctr Pune Maharashtra India;

Bharati Vidyapeeth Deemed Univ Dept Pharmacol Poona Coll Pharm Pune Maharashtra India;

Bharati Vidyapeeth Deemed Univ Dept Pharmacol Poona Coll Pharm Pune Maharashtra India;

SVKMs Inst Pharm Dept Pharmaceut Chem Survey 499 Plot 03 Mumbai 424001 Maharashtra India;

MES Abasaheb Garware Coll Dept Chem Post Grad &

Res Ctr Pune Maharashtra India;

Bharati Vidyapeeth Deemed Univ Poona Coll Pharm R&

D Ctr Pharmaceut Sci &

Appl Chem Pune;

Bharati Vidyapeeth Deemed Univ Dept Pharmacol Poona Coll Pharm Pune Maharashtra India;

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正文语种 eng
中图分类药理学 ;
关键词
1-phenyl-5-hydroxy-7; (4"-hydroxy-3"methoxyphenyl); heptane-3-one (i.e. 5-HPH); Alpinia officinarum (Zingiberaceae); Complete Freund's adjuvant-induced arthritis; Interleukin (IL)-1 beta; Molecular docking; Oxidative stress; Tumor necrosis factor (TNF)-alpha;

机译：1-苯基-5-羟基-7;（4“ - 羟基-3”甲氧基苯基）;庚烷-3-一（即5-HPH）;alpinia Officinarum（Zingiberaceae）;完全弗氏佐剂诱导的关节炎;白细胞介素（IL） -1 beta;分子对接;氧化应激;肿瘤坏死因子（TNF） - alpha;

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专利

1. Diarylheptanoid, a constituent isolated from methanol extract of Alpinia officinarum attenuates TNF-alpha level in Freund's complete adjuvant-induced arthritis in rats [J] . Honmore Varsha S., Kandhare Amit D., Kadam Parag P., Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2019 ,第期

机译：二芳基肽，从甲醇提取物中分离的alpinia Officinarum的组成部分衰减弗氏完全佐剂诱导的关节炎的TNF-α水平
2. Anti-inflammatory, anti-nociceptive, and anti-psychiatric effects by the rhizomes of Alpinia officinarum on complete Freund's adjuvant-induced arthritis in rats. [J] . Lee J, Kim KA, Jeong Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2009 ,第2期

机译：Alpinia officinarum的根茎对大鼠完全弗氏佐剂诱发的关节炎具有抗炎，抗伤害和抗精神病作用。
3. Anti-arthritic activity of methanol extract of Cyathocline purpurea (whole plant) in Freund's complete adjuvant-induced arthritis in rats [J] . Gopal V. Bihani, Supada R. Rojatkar, Subhash L. Bodhankar Biomedicine & aging pathology . 2014 ,第3期

机译：紫杉醇（整个植物）甲醇提取物对弗氏完全佐剂诱发的大鼠关节炎的抗关节炎作用
4. Separation and Bioactivity of Diarylheptanoids from Lesser Galangal (Alpinia officinarum) [C] . Zhihua Liu, M. Mohamed Rafi, Nanqun Zhu, Symposium on food factors in health promotion and disease prevention . 2003

机译：较少伽兰（Alpinia Officinarum）的二芳基肽的分离和生物活性
5. A Peptide Comprising the Src-Interacting Domain of NADH Dehydrogenase Subunit 2 Alleviates Complete Freund's Adjuvant-Induced Allodynia in Rats. [D] . Barszczyk, Andrew. 2010

机译：包含NADH脱氢酶亚基2 Src相互作用域的肽减轻大鼠完全弗氏佐剂诱导的异常性疼痛。
6. Er Miao San a traditional Chinese herbal formula attenuates complete Freund’s adjuvant-induced arthritis in rats by regulating Th17/Treg cells [O] . Xing Dai, Dongping Yang, Jinping Bao, 2020

机译：二妙散一种传统的中草药配方通过调节Th17 / Treg细胞来减轻弗氏完全佐剂诱导的关节炎
7. Correction to: Moringa oleifera leaf extracts attenuate Complete Freund’s adjuvant-induced arthritis in Wistar rats via modulation of inflammatory and oxidative stress biomarkers [O] . Ammara Saleem, Mohammad Saleem, Muhammad Furqan Akhtar, 2019

机译：矫正：Moringa Oleifera叶子提取物通过调制炎症和氧化应激生物标志物在Wistar大鼠中衰减完整的弗氏佐剂诱导的关节炎

Diarylheptanoid, a constituent isolated from methanol extract of Alpinia officinarum attenuates TNF-alpha level in Freund's complete adjuvant-induced arthritis in rats

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