Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors (vol 59, pg 5879, 2016)

Reis Joana; Cagide Fernando; Chavarria Daniel; Silva Tiago; Fernandes Carlos; Gaspar Alexandra; Uriarte Eugenio; Remiao Fernando; Alcaro Stefano; Ortuso Francesco; Borges Fernanda

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Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors (vol 59, pg 5879, 2016)

机译：对旧目标的新化学实体发现：关于铬基单胺氧化酶B（MAO-B）抑制剂的铅优化的见解（Vol 59，PG 5879,2016）

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《Journal of Medicinal Chemistry》 |2018年第11期|共1页
作者
Reis Joana; Cagide Fernando; Chavarria Daniel; Silva Tiago; Fernandes Carlos; Gaspar Alexandra; Uriarte Eugenio; Remiao Fernando; Alcaro Stefano; Ortuso Francesco; Borges Fernanda;
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正文语种 eng
中图分类药学;
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1. Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors (vol 59, pg 5879, 2016) [J] . Reis Joana, Cagide Fernando, Chavarria Daniel, Journal of Medicinal Chemistry . 2018,第11期

机译：对旧目标的新化学实体发现：关于铬基单胺氧化酶B（MAO-B）抑制剂的铅优化的见解（Vol 59，PG 5879,2016）
2. Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors [J] . Joana Reis, Fernando Cagide, Martín Estrada Valencia, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2018,第期

机译：用于阿尔茨海默病的多目标定向配体：发现铬基单胺氧化酶/胆碱酯酶抑制剂
3. Discovery of a Novel Class of Potent Coumarin Monoamine Oxidase B Inhibitors: Development and Biopharmacological Profiling of 7-[(3-Chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one Methanesulfonate (NW-1772) as a Highly Potent, Selective, Reversible, and Orally Active Monoamine Oxidase B Inhibitor [J] . Pisani L, Muncipinto G, Miscioscia TF, Journal of Medicinal Chemistry . 2009,第21期

机译：一类新型强力香豆素单胺氧化酶B抑制剂的发现：7-[（3-氯苄基）氧基] -4-[（甲基氨基）甲基] -2H-铬-2-酮甲烷磺酸盐（NW-1772）的开发和生物药理学分析）作为高效，选择性，可逆和口服活性单胺氧化酶B抑制剂
4. Discovery of N-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel selective and competitive indole-based lead inhibitor for human monoamine oxidase B [O] . Ahmed Elkamhawy, Sora Paik, Hyeon Jeong Kim, 2020

机译：发现N-（1-（3-氟苯甲酰）-1H-吲哚-5-基）吡嗪-2-甲酰胺：用于人单胺氧化酶B的新型选择性和竞争性吲哚基铅抑制剂
5. Correction to Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors [O] . Joana Reis, Fernando Cagide, Daniel Chavarria, 2018

机译：对旧目标新化学实体的发现矫正：关于铬基单胺氧化酶B（MAO-B）抑制剂的铅优化的见解

Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors (vol 59, pg 5879, 2016)

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